Hormone-Active Ovarian Steroid Cell Tumor in a 2-Year-Old Girl

    Susann Blüher, Toralf Bernig, Martin Kaiser, Dominik T. Schneider, Christian Kunze, Katja Ronstedt, Christine Fathke, Amica Corda Müller-Nedebock, Pablo Villavicencio‐Lorini, Jessica I. Hoell
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    TLDR A rare ovarian tumor in a 2-year-old girl was successfully removed, normalizing her hormone levels.
    This case study reports on a rare instance of a hormone-active ovarian steroid cell tumor in a 2-year-old girl, presenting with symptoms of virilization and precocious puberty. The tumor, located in the left ovary, was identified through elevated hormone levels and imaging techniques. Surgical removal of the tumor led to a rapid decrease in hormone levels to prepubertal values. The tumor was classified as clinical stage Ia, and the patient was monitored through clinical, biochemical, and sonographical controls without chemotherapy. The study highlights the rarity of such tumors in infancy and discusses follow-up data up to 18 months post-surgery.
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