TLDR A 68-year-old woman developed male traits due to a tumor in her ovary, which was removed, returning her hormone levels to normal.
In 2018, a case was reported of a 68-year-old woman who developed male sexual characteristics, a condition known as virilism, due to an ovarian steroid cell tumor. The woman presented with androgenic alopecia, clitoromegaly, and increased muscle mass. Laboratory tests revealed both ovarian and adrenal hyperandrogenism, with elevated levels of androgen precursors, similar to congenital adrenal hyperplasia. Imaging techniques confirmed a left adnexal mass, and a laparoscopic bilateral salpingo-oophorectomy was performed. Histopathology confirmed the diagnosis of an ovarian steroid cell tumor. After the surgery, the woman's circulating androgen levels and their precursors returned to normal. The study concluded that a detailed anamnesis and physical examination are crucial for the correct diagnosis in a woman with hyperandrogenism, regardless of her circulating androgen profile.
4 citations,
December 2012 in “Arquivos Brasileiros De Endocrinologia E Metabologia” A postmenopausal woman's masculine symptoms improved after surgery for a hormone-producing ovarian tumor.
9 citations,
January 1997 in “Gynecological Endocrinology” The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
35 citations,
March 2012 in “Experimental and Clinical Endocrinology & Diabetes” The conclusion is that accurately identifying the cause of high androgen levels in women with PCOS is crucial and requires specific tests.
research Acne
81 citations,
January 2002 in “American journal of clinical dermatology” Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.
13 citations,
June 1989 in “Pediatric clinics of North America/The Pediatric clinics of North America” The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.
151 citations,
December 2004 in “Annals of the New York Academy of Sciences” Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.
