Postmenopausal Hyperandrogenism Due to Rare Ovarian Tumor

    October 2024 in “ Journal of the Endocrine Society ”
    Michael Salim, Sandhyarani Dasaraju, Y. Lee, Soha Afzal, Britt Erickson, Mahmoud Khalifa, Lynn A. Burmeister
    Image of study
    TLDR Rare ovarian tumors can cause hyperandrogenism, even if imaging appears normal.
    A 66-year-old postmenopausal woman with a history of diabetes and breast cancer presented with worsening alopecia and other signs of hyperandrogenism. Laboratory tests revealed elevated testosterone and androstenedione levels. Imaging showed a stable left adrenal nodule, but no ovarian abnormalities. Adrenal and ovarian vein sampling indicated the ovaries as the testosterone source. A bilateral salpingo-oophorectomy (BSO) was performed, revealing bilateral Leydig cell tumors and a left ovarian Brenner tumor. Post-surgery, the patient's alopecia resolved, and testosterone levels normalized. This case highlights the diagnostic challenge of postmenopausal hyperandrogenism due to rare ovarian tumors.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 32 results

      community Summaries of Finasteride Studies

      in Research/Science  20 upvotes 1 month ago
      Finasteride is effective in promoting hair growth and reversing hair miniaturization in men with androgenetic alopecia, with improvements seen in various studies over different durations. Some users report initial side effects like ball ache, which often resolve as the body adjusts.

      community Losing Hair on Dutasteride? You might have LPP

      in Research/Science  96 upvotes 4 months ago
      Men with hair loss might have lichen planopilaris (LPP), which can mimic androgenetic alopecia, leading to misdiagnosis and ineffective treatment with finasteride or dutasteride. Proper diagnosis, including biopsies, is crucial to distinguish between androgenetic alopecia and conditions like LPP.

      community 9 months progress looks good to me

      in Is this regrowth?  86 upvotes 11 months ago
      A 35-year-old male reported positive hair regrowth after 9 months using oral dutasteride 0.5mg and oral minoxidil 5mg daily. A reply emphasized the importance of commitment and consistency for hair regrowth.

    Similar Research

    5 / 1000+ results