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Leflunomide and methotrexate are similarly effective for rheumatoid arthritis but have different side effects.

The lowest effective dose of Botox for detrusor sphincter dyssynergia is between 75-100 units.

Early diagnosis and treatment of achalasia and hyperthyroidism improve patient outcomes.

A woman in Sri Lanka was diagnosed with lupus after presenting with protein loss from the gut and other symptoms.

A woman with ectopic Cushing's syndrome and COVID-19 passed away despite treatment.

Appropriate zinc levels may help prevent hair loss in university students.

Diet and supplements can significantly affect acne, with some foods and nutrients reducing and others worsening it.

Understanding drug interactions, side effects, and patient-specific factors is crucial for effective dermatological care.

Oral zinc sulphate is an effective and safe treatment for thallium poisoning.

The conclusion suggests a new treatment for infantile hemangiomas and a potential target for hair loss treatment.

Thyroid disease can cause hair loss and treating thyroid problems might help with hair disorders.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Doxil is an effective, modified chemotherapy drug with a unique toxicity profile and shows promise in treating certain cancers.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Testosterone therapy improves physical function, strength, and body composition in older men with low testosterone levels.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

Corticosteroids, especially prednisone, improve short-term muscle strength in Duchenne muscular dystrophy but have manageable side effects.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.

Lichen Planus is a less common condition affecting skin and mucous membranes, with various types and associated risk factors, challenging to diagnose, significantly impacts life quality, and may have a risk of cancerous changes in oral lesions.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

Iron deficiency may be related to hair loss, but there's not enough evidence to recommend iron screening or supplements for all hair loss patients.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.

Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.

Humans lost body hair relatively recently in evolution.

Cancer cells often have more copies of TERT and TERC genes, which helps them grow and could affect patient outcomes.