Flavonoids as Potential Wound-Healing Molecules: Emphasis on Pathways Perspective

    February 2023 in “ International Journal of Molecular Sciences ”
    Nabilah Zulkefli, Che Nur Mazadillina Che Zahari, Nor Hafiza Sayuti … Murni Nazira Sarian
    Studysummary This review compiled evidence suggesting that flavonoids may promote skin wound healing due to their anti-inflammatory, angiogenesis, re-epithelialization, and antioxidant properties, while also discussing current limitations and future prospects for these compounds as wound-healing agents.
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    Research cited in this study 5

    1. Dual-Action Icariin-Containing Thermosensitive Hydrogel for Wound Macrophage Polarization and Hair Follicle Neogenesis Frontiers in Bioengineering and Biotechnology · 2022
    2. Flavonoids with Two Hydroxyl Groups in the B-Ring Promote Pigmented Hair Regeneration Biological & Pharmaceutical Bulletin · 2019
    3. Wound Healing: A Cellular Perspective Physiological Reviews · 2018
    4. Cutaneous Scarring: Basic Science, Current Treatments, and Future Directions Advances in wound care · 2016
    5. Hedgehog Signaling Is Essential For Normal Wound Healing Wound Repair and Regeneration · 2008