January 2016 in “Electronic Theses of LMU Munich (Ludwig-Maximilians-Universität München)” FDG PET/CT can improve cancer treatment plans in dogs.
7 citations
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March 2022 in “International Journal of Molecular Sciences” This study found that FGF21 suppresses inflammation induced by C. acnes in both human skin cells and mouse models, suggesting potential use in acne treatment.
9 citations
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January 1997 in “Endocrine Journal” This study found a significant association between patients' sex of rearing and external genitalia in those with gonadal dysgenesis, while noting lower testosterone levels compared to controls.
1 citations
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August 2022 in “International Journal of Molecular Sciences” In this study, FGF12 was found to promote hair growth in mice by inducing the anagen phase of hair follicles, suggesting potential for hair loss therapy.
5 citations
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November 2020 in “Dermatologic Therapy” This study found that a mutant form of the FGF5s protein, FGF5sC93S, significantly increased hair count after 24 weeks of application on human scalps, suggesting its potential as a hair growth treatment.
44 citations
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April 2006 in “Expert opinion on drug safety” This review describes the approved use and adverse effects of gefitinib in patients with advanced non-small cell lung cancer, without presenting new clinical findings.
January 2020 in “Global dermatology” This study found that iontophoresis with growth factor cocktail including fibroblast growth factor 5-short significantly increased hair density in patients with androgenetic alopecia over 24 weeks.
June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A substance called FGF9 from certain immune cells can trigger new hair growth during wound healing in mice, but humans may not have the same response due to fewer of these cells.
4 citations
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June 1998 in “The Journal of Clinical Endocrinology & Metabolism” This study found that keratinocyte growth factor is a potent mitogen in human hyperplastic prostate cells, suggesting it plays an important role in prostate growth by acting in a paracrine manner.
The researchers reported that PEG-FGF2 conjugates, particularly Compound 6, significantly enhanced stability, proliferation, migration, and wound healing activity compared to native FGF2, despite some reduction in bioactivity near crucial binding domains.
This study found that FGF5 alternative spliceosomes inhibit dermal papilla cell proliferation and regulate hair follicle growth-related gene expression, impacting hair follicle development in rabbits.
3 citations
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January 2018 in “International Journal of Trichology” The authors concluded that their new grading system can effectively classify early female pattern hair loss and evaluate treatment progress.
In this study, researchers found that Fgf21 knockout mice exhibited delayed hair follicle cycling compared to wild-type mice, potentially due to altered miRNA interactions affecting Vezf1 and Map3k1 expression, providing insights into the molecular regulation of hair growth.
8 citations
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October 2022 in “International Journal of Molecular Sciences” This study found that CLD-hFGF2 hydrogels improved healing in deep second-degree burn wounds more effectively than hydrogels alone or direct administration of CLD-hFGF2.
3 citations
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December 2024 in “Stem Cell Reports” In this study, researchers observed that low levels of fucose-binding lectin staining characterize limbal epithelial progenitor cells, which maintain a high proliferative capacity and may be enhanced by inhibiting fucosylation, offering insights for regenerative therapy of the limbal stem cell niche.
This study presents the G4 transgenic mouse model, which suggests a direct link between polycystic ovary syndrome and the Gm10800 gene, offering a valuable tool for understanding the disease and testing treatments.
1 citations
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June 2016 in “FEBS open bio” This study reports that topical fish oil treatment in GsdmA3 Dfl/+ mice increased cellular proliferation and macrophages but did not affect COX-2 expression related to psoriasis-like skin changes.
41 citations
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January 1992 in “Journal of medical genetics” This study described seven male patients and six female carriers of keratosis follicularis spinulosa decalvans, highlighting distinct dermatological and ophthalmic markers including follicular hyperkeratosis and corneal dystrophy.
42 citations
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September 2015 in “Gene” This study demonstrated that FGF5s acts as an inhibitor of FGF5 in regulating hair growth cycles in cashmere goat dermal papilla cells.
39 citations
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July 1993 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that daily injections of basic and acidic fibroblast growth factor in newborn mice significantly delayed hair follicle development within the treatment area, while epidermal growth factor affected the entire body coat and caused skin hyperkeratinization.
July 2022 in “http://isrctn.com/” Adding a cosmetic gel with caffeine, taurine, and growth factors to standard hair loss treatments could improve results.
12 citations
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July 2015 in “Experimental Dermatology” This study found that overexpression of Gsdma3 in mice led to epidermal hyperplasia, skin inflammation, and hair growth defects, suggesting gain-of-function mutations in Gsdma3 cause these conditions.
1 citations
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October 2020 in “Research Square (Research Square)” This study identified a 505-bp indel variant in the FGF5 gene associated with cashmere growth in goats, which may serve as a molecular marker in cashmere goat breeding programs.
32 citations
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March 2014 in “PLOS ONE” This study demonstrates that FMOD deficiency in mice alters TGF-β ligand and receptor expression during wound healing stages, leading to delayed wound closure and increased scar size.
7 citations
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June 2011 in “Movement Disorders” A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.
1 citations
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January 2015 in “Journal of clinical case reports” This case report describes two siblings with Keratosis Follicularis Spinulosa Decalvans, illustrating its manifestations in a 9-year-old boy and a 5-year-old girl.
January 2026 in “Dermatology and Therapy” This study suggests that using UVFD to examine non-pigmented facial lesions can potentially enhance diagnostic accuracy and reduce unnecessary biopsies.
June 2026 in “Frontiers in Oncology” In this study, researchers found that deficiencies in Gsdma1/2/3 significantly inhibited the initiation and progression of cutaneous squamous cell carcinoma (cSCC) in mice, suggesting GSDMA's role in promoting cSCC proliferation and its potential as a therapeutic target.
January 2003 in “Jiefangjun yixue zazhi” In this study, the researchers observed that the expression of certain growth factors and their receptors increases with gestational age, implying a role in skin development, structure maintenance, and wound healing.
237 citations
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June 2013 in “Nature Medicine” This study found that fibroblast growth factor 9, initially secreted by γδ T cells, plays a key role in modulating hair follicle regeneration in mice after skin wounds.