Effect of Iontophoresis with Growth Factor Cocktail Containing Fibroblast Growth Factor 5-Short Applied to the Scalp in Patients with Androgenetic Alopecia – A Split Study

The study evaluated the effect of iontophoresis with a growth factor cocktail (GFC) containing fibroblast growth factor 5-short (FGF5s) on hair growth in 21 patients with androgenetic alopecia (AGA). Over 24 weeks, the right side of the scalp was treated with GFC and the left side with saline. Results showed a significant increase in hair density from 179.2±5.5/cm² to 193.9±5.3/cm² (p<0.0001) and a slight increase in hair diameter from 54.9±2.3 mm to 55.3±2.3 mm (p<0.0565) on the GFC-treated side, while the saline-treated side showed no significant changes. The study concluded that iontophoresis with GFC including FGF5s was effective for hair growth in AGA patients, but further research is needed to assess long-term efficacy.