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GlossaryFibroblast Growth Factor 5 (FGF5)

protein that inhibits hair growth by signaling phase transition

Fibroblast Growth Factor 5 (FGF5) is a protein that plays a crucial role in regulating the hair growth cycle. Specifically, it acts to inhibit hair growth by signaling the transition from the growth phase (anagen) to the regression phase (catagen), which can lead to shorter hair growth periods and potentially contribute to conditions like alopecia.

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research Effect of Iontophoresis with Growth Factor Cocktail Containing Fibroblast Growth Factor 5-Short Applied to the Scalp in Patients with Androgenetic Alopecia – A Split Study

January 2020 in “Global dermatology”

Iontophoresis with a growth factor cocktail helps hair growth in patients with androgenetic alopecia.

Fibroblast Growth Factor 5-Short (FGF5s) Inhibits the Activity of FGF5 in Primary and Secondary Hair Follicle Dermal Papilla Cells of Cashmere Goats

research Fibroblast Growth Factor 5-Short (FGF5s) Inhibits the Activity of FGF5 in Primary and Secondary Hair Follicle Dermal Papilla Cells of Cashmere Goats

42 citations, September 2015 in “Gene”

FGF5s can block the effects of FGF5, which may help control hair growth in cashmere goats.

research Expression and Function of FGF5 Isoform in Hair Growth

1 citations, February 2021 in “Scholars international journal of anatomy and physiology”

Different forms of FGF5 either promote or inhibit hair growth.

research Therapeutic Effects of Growth Factor Cocktail (CellcurinTM) Containing FGF5s (Fibroblast Growth Factor 5 Short) and NMN (Nicotinamide Mononucleotide) in Patients with Androgenetic Alopecia: A Split Study

January 2020 in “Global dermatology”

The growth factor cocktail significantly increased hair growth in patients with androgenetic alopecia.

research Molecular Cloning, Characterization, and Expression of Sheep FGF5 Gene

11 citations, October 2014 in “Gene”

Researchers identified a new variant of the FGF5 gene in sheep that affects hair length.

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community Mystery compound found to be safe and effective at treating hair loss. Details in comments.

in Technology 6 upvotes 6 years ago

A compound called MTP3 from the Monoterpene family was found to be safe and highly effective at treating hair loss by inhibiting the FGF5 gene, but its identity is undisclosed for commercial reasons. No specific treatments like Minoxidil, finasteride, or RU58841 were discussed.

community Lion Mane Part 2: Microneedling with Topicals, beneficial compounds, maybe?

in Microneedling 1 upvotes 9 months ago

The conversation discusses microneedling techniques and the use of Minoxidil, copper peptides, EGF, FGF, ceramides, and hydration serums to enhance hair growth. It explores optimizing scalp conditions and the potential benefits of various compounds in conjunction with microneedling.

community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

in Research/Science 92 upvotes 2 years ago

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

community DIY treatment... Shedding completely stopped after 1.5 yrs

in Treatment 250 upvotes 3 years ago

Vitamin C mixed with shampoo stopped shedding and promoted hair regrowth after 1.5 years. Both the person and their wife experienced significant hair loss reduction with this method.