Effect of Cysteine-Free Human Fibroblast Growth Factor-5s Mutant (FGF5sC93S) on Hair Growth

    November 2020 in “ Dermatologic Therapy ”
    Yu Jin Kim, Narae Jung, Nayoung Kim … Chun‐Hyung Kim
    Studysummary This study found that a mutant form of the FGF5s protein, FGF5sC93S, significantly increased hair count after 24 weeks of application on human scalps, suggesting its potential as a hair growth treatment.
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    Research cited in this study 10

    1. Controversies in the Treatment of Androgenetic Alopecia: The History of Finasteride Dermatologic Therapy · 2018
    2. CRISPR/Cas9-Mediated Loss of FGF5 Function Increases Wool Staple Length in Sheep ˜The œFEBS journal · 2017
    3. The Study on Biological Function of Keratin 26, a Novel Member of Liaoning Cashmere Goat Keratin Gene Family PloS one · 2016
    4. Androgenetic Alopecia: An Update Of Treatment Options Drugs · 2016
    5. Fibroblast Growth Factor 5-Short (FGF5s) Inhibits the Activity of FGF5 in Primary and Secondary Hair Follicle Dermal Papilla Cells of Cashmere Goats Gene · 2015
    6. Constitutive Activation of Stat3 in Mouse Epidermis Is Linked to Hair Deficiency and Cytoskeletal Network Damage Experimental Dermatology · 2015
    7. Resting No More: Redefining Telogen, the Maintenance Stage of the Hair Growth Cycle Biological Reviews · 2014
    8. Molecular Cloning, Characterization, and Expression of Sheep FGF5 Gene Gene · 2014
    9. K6irs1, K6irs2, K6irs3, And K6irs4 Represent The Inner-Root-Sheath-Specific Type II Epithelial Keratins Of The Human Hair Follicle Journal of Investigative Dermatology · 2003
    10. Growth Factors in Hair Organ Development and the Hair Growth Cycle Dermatologic Clinics · 1996

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