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    Did you mean Genetic Loci?
    Glossary Genetic Loci

    specific location on a chromosome for a particular gene

    A genetic locus (plural: loci) is a specific, fixed position on a chromosome where a particular gene or genetic marker is located. Think of it as an address for a gene within the vast neighborhood of the genome. This location is crucial for understanding genetic inheritance and variations, as it helps scientists pinpoint where specific traits or disorders, such as those related to alopecia, are encoded in our DNA.

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    1. Genetic Variation at the MC1R Locus and the Time since Loss of Human Body Hair Current anthropology · 2004 · 152 citations
    2. A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females Nature Communications · 2015 · 103 citations
    3. A new locus for hereditary hypotrichosis simplex maps to chromosome 13q12.12∼12.3 in a Chinese family Journal of Cutaneous Pathology · 2010 · 7 citations
    4. Mapping of a novel locus for keratosis follicularis squamosa on chromosome 7p14.3–7p12.1 Journal of Dermatological Science · 2010 · 4 citations
    5. Male-pattern baldness susceptibility locus at 20p11 Nature Genetics · 2008 · 111 citations
    6. Genome-wide association study identifies a new locus JMJD1C at 10q21 that may influence serum androgen levels in men 2012 · 78 citations
    7. Fine mapping of the human <i>AR/EDA2R</i> locus in androgenetic alopecia British Journal of Dermatology · 2010 · 28 citations
    8. Association between the D19S884 marker at the insulin receptor gene locus and polycystic ovary syndrome Fertility and Sterility · 2003 · 48 citations
    9. Genome-wide Scan and Fine-Mapping Linkage Study of Androgenetic Alopecia Reveals a Locus on Chromosome 3q26 American Journal of Human Genetics · 2008 · 62 citations
    10. Vesicle Formation and Follicular Root Sheath Separation in Mice Homozygous for Deleterious Alleles at the Balding (bal) Locus 1997 · 38 citations
    11. Hair of the Dog: Identification of a Cis-Regulatory Module Predicted to Influence Canine Coat Composition Genes · 2019 · 14 citations
    12. A New Clinical Variant of Hereditary Localized Alopecia: Report of a Chinese Family Mapped to Chromosome 2p25.1–2p23.2 2007 · 2 citations
    13. A locus on distal chromosome 10 (ahl4) affecting age-related hearing loss in A/J mice Neurobiology of aging · 2008 · 62 citations
    14. The slick hair coat locus maps to chromosome 20 in Senepol-derived cattle Animal Genetics · 2007 · 51 citations
    15. Genetic Variants at 20p11 Confer Risk to Androgenetic Alopecia in the Chinese Han Population PLOS ONE · 2013 · 9 citations
    16. Investigation of the male pattern baldness major genetic susceptibility loci AR/EDA2R and 20p11 in female pattern hair loss British Journal of Dermatology · 2012 · 38 citations
    17. Association study reveals a susceptibility locus with male pattern baldness in the Han Chinese population Frontiers in Genetics · 2024
    18. Whole-genome SNP genotyping mapped a novel locus for hereditary hypotrichosis on chromosome 2q31.1–q32.2 Journal of Dermatological Science · 2015
    19. Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31 Nature Communications · 2013 · 106 citations
    20. W locus alleles of the KIT Gene in Turkish Van Cats and Their Association with Certain Phenotypes Van Sağlık Bilimleri Dergisi · 2022
    21. The Phenotypic and Genotypic Spectra of Ichthyosis With Confetti Plus Novel Genetic Variation in the 3′ End of<i>KRT10</i> JAMA dermatology · 2014 · 22 citations
    22. Patched-assoziierte Tumoren: Modifikatorgene und Pathogenese 2022
    23. A family of type I keratin genes and the homeobox-2 gene complex are closely linked to the rex locus on mouse chromosome 11 Genomics · 1989 · 49 citations
    24. Joint study of the associations of HLA‐B and the transmembrane short tandem repeat polymorphism of MICA protein with alopecia areata shows independent associations of both with the disease Clinical and Experimental Dermatology · 2020 · 7 citations
    25. Genetic Variation in the Human Androgen Receptor Gene Is the Major Determinant of Common Early-Onset Androgenetic Alopecia American Journal of Human Genetics · 2005 · 195 citations
    26. Genetics of blond hair Nature Genetics · 2012
    27. Evidence for a functional interaction of WNT10A and EBF1 in male-pattern baldness PLoS ONE · 2021 · 12 citations
    28. Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria PLOS Genetics · 2018 · 308 citations
    29. Genetic association of <i>HLA‐DQB1</i> and <i>HLA‐DRB1</i> polymorphisms with alopecia areata in the Italian population British Journal of Dermatology · 2011 · 35 citations
    30. Corneodesmosin: Structure, Function and Involvement in Pathophysiology The Open Dermatology Journal · 2010 · 2 citations