Association Study Reveals a Susceptibility Locus With Male Pattern Baldness in the Han Chinese Population

    September 2024 in “ Frontiers in Genetics ”
    Li Yang, Huang He, Bo Liang … Xuejun Zhang
    Studysummary In this study, researchers found a significant association between the rs13405699 SNP at 2q31.1 and male pattern baldness among Han Chinese men, suggesting genetic influence on this condition in this population.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on public-pages-files-2025.frontiersin.org →
    Discuss this study in the Community →

    Research cited in this study 13

    1. Effects of Photobiomodulation at Various Irradiances on Normal and Dihydrotestosterone-Treated Human Hair Dermal Papilla Cells In Vitro Journal of Biophotonics · 2023
    2. The First Broad Replication Study of SNPs and a Pilot Genome-Wide Association Study for Androgenetic Alopecia in Asian Populations Journal of Cosmetic Dermatology · 2022
    3. 5-Bromo-3,4-Dihydroxybenzaldehyde Promotes Hair Growth Through Activation of Wnt/β-Catenin and Autophagy Pathways and Inhibition of TGF-β Pathways in Dermal Papilla Cells Molecules · 2022
    4. Hair Growth-Promotion Effects at the Cellular Level and Antioxidant Activity of the Plant-Based Extract Phyllotex Heliyon · 2021
    5. Impairment of Autophagy May Be Associated with Follicular Miniaturization in Androgenetic Alopecia by Inducing Premature Catagen Journal of Dermatology · 2020
    6. Examination of Androgenetic Alopecia with Serum Biomarkers Journal of Cosmetic Dermatology · 2020
    7. GWAS for Male-Pattern Baldness Identifies 71 Susceptibility Loci Explaining 38% of the Risk Nature Communications · 2017
    8. Meta-Analysis Identifies Novel Risk Loci and Yields Systematic Insights into the Biology of Male-Pattern Baldness Nature communications · 2017
    9. An Investigation of Crosstalk Between Wnt/β-Catenin and Transforming Growth Factor-β Signaling in Androgenetic Alopecia Medicine · 2016
    10. Genetic Variants at 20p11 Confer Risk to Androgenetic Alopecia in the Chinese Han Population PLOS ONE · 2013
    11. Androgen Receptor Transactivity Is Potentiated by TGF-β1 Through Smad3 but Checked by Its Coactivator Hic-5/ARA55 in Balding Dermal Papilla Cells Journal of Dermatological Science · 2011
    12. Prevalence of Androgenetic Alopecia in China: A Community-Based Study in Six Cities British Journal of Dermatology · 2010
    13. Perifollicular Fibrosis: Pathogenetic Role in Androgenetic Alopecia Biological & Pharmaceutical Bulletin · 2006