Symposium Proceedings of the 4th Intercontinental Meeting of Hair Research Societies: The World of Hair 2004
November 2005
in “
Journal of Investigative Dermatology Symposium Proceedings
”
hair follicle dermis cells NF-kappa-B signalling keratin associated proteins BNP MC-1R signalling pathways TRP-2 expression androgenetic alopecia androgen target cells alopecia areata neurotrophins CD8 cells neuroendocrinology pilosebaceous unit IGF-1 TGF-B targeted follicular therapy hair follicle cells NF-kappa-B keratin proteins MC-1R TRP-2 male pattern baldness androgen cells autoimmune hair loss nerve growth factors immune cells hormonal control hair follicle unit insulin-like growth factor 1 transforming growth factor beta follicle therapy
TLDR The 2004 hair research meeting presented new findings on hair cell differentiation, genetic factors in hair loss, hair pigmentation, and potential targeted therapies.
The 4th Intercontinental Meeting of Hair Research Societies in 2004 was the largest gathering of its kind, with 514 participants from 40 countries. The meeting featured a comprehensive scientific program with 100 oral and 160 poster presentations on hair physiology, pathogenesis, and therapy. Key findings included the potential of hair follicle dermis cells to differentiate into various cell types, which could lead to new therapeutic approaches. Genetic research highlighted the role of NF-kappa-B signalling in hair loss disorders and identified over 80 keratin associated proteins. Studies on hair pigmentation revealed interactions between BNP and MC-1R signalling pathways and the independence of black and brown hair color from TRP-2 expression. Androgenetic alopecia was recognized as the most common hair growth disorder, with new insights into the characteristics of androgen target cells. The genetic basis of alopecia areata remains largely unknown, but new research suggested the involvement of neurotrophins and CD8 cells in its development. Endocrinological studies pointed to the neuroendocrinology of the pilosebaceous unit and the role of IGF-1 and TGF-B in hair growth. The meeting emphasized the importance of targeted follicular therapy and the potential benefits for patients from the advancements in hair research. The next meeting was scheduled for 2007 in Vancouver, Canada.
