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The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

Transplanting growing hair follicles into scars can help regenerate and improve scar tissue.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

CREB, a protein that can promote cancer traits, is controlled by β-catenin in skin cancer cells.

The document concludes that ERBB2 mutations are common in extramammary Paget disease and may respond to systemic treatments like cancer immunotherapy.

A new mutation in the human glucocorticoid receptor reduces its function and causes resistance to glucocorticoids.

Special immune cells called Regulatory T cells help control skin inflammation and repair in various skin diseases.

Genetic data can predict male-pattern baldness with moderate accuracy, especially for early-onset cases in some European men.

New treatments for advanced skin cancer are improving patient outcomes, but drug resistance and finding the right treatment combinations are still big challenges.

Skin problems can be signs of hormone-related disorders and recognizing them early is important for treatment.

A peptide called DPS-1 helps human scalp cells grow and stimulates hair growth in mice.

Tissue-derived extracellular vesicles are crucial for cancer diagnosis, prognosis, and treatment.

Myoepithelial cells can repair airways after severe injury.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Hair follicle development and microbes help regulatory T cells gather in newborn skin.

Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.

Rhodococcus equi causes severe pneumonia in young foals, and effective vaccines are needed due to foals' weak immune responses.

Women with PCOS are more than twice as likely to develop nonalcoholic fatty liver disease.

The document concludes that understanding sulfation biology is crucial for creating treatments due to its importance in biological functions and disease.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.

Skin stem cells maintain and repair the outer layer of skin, with some types being essential for healing wounds.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Tooth papilla cells can help regenerate hair follicles and grow hair.

Baricitinib helps treat several diseases, including COVID-19, but has side effects and needs careful monitoring.

Hair loss in male pattern baldness involves muscle degeneration and increased scalp fat.