research A New Clinical Variant of Hereditary Localized Alopecia: Report of a Chinese Family Mapped to Chromosome 2p25.1–2p23.2
A new type of hereditary hair loss in a Chinese family is linked to chromosome 2p25.1–2p23.2.
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research Exosomal MicroRNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation
Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
research Genetic Basis of Polycystic Ovary Syndrome
The document concludes that PCOS has a strong genetic component, but more research is needed to fully understand the specific genes involved.
research Analysis of the Human Diseasome Using Phenotype Similarity Between Common, Genetic, and Infectious Diseases
The study found that diseases can be grouped by symptoms and that the accuracy of predicting disease-related genes varies with the data source.
research Network-Based Approaches Reveal Potential Therapeutic Targets for Host-Directed Antileishmanial Therapy Driving Drug Repurposing
Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.
research Association of mtDNA M/N Haplogroups with Systemic Lupus Erythematosus: A Case-Control Study of Han Chinese Women
The mtDNA N haplogroup is linked to a higher risk of late-onset lupus and specific symptoms in Han Chinese women.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research Androgenetic Alopecia: Overview, Epidemiology, Pathophysiology, and Treatment
Various treatments exist for hair loss, but more research is needed for better options.
research Integrated miRNA-mRNA Analysis Reveals Regulatory Pathways Underlying the Curly Fleece Trait in Chinese Tan Sheep
Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.
research Signal Integrator Function of CXXC5 in Cancer
CXXC5 can both suppress and promote cancer, making it a complex target for treatment.
research Ectoin Attenuates Cortisone-Induced Skin Issues by Suppression of GR Signaling and the UVB-Induced Overexpression of 11β-HSD1
Ectoin helps prevent cortisone-induced skin problems and supports skin health.
research DNA Microarray and Bioinformatic Analysis Reveals the Potential of Whale Oil in Enhancing Hair Growth in a C57BL/6 Mice Dorsal Skin Model
Whale oil significantly promotes hair growth and may be a safe, effective alternative to minoxidil.
research Dermal Fibroblasts in Cutaneous Development and Healing
Skin cells called dermal fibroblasts are important for skin growth, hair growth, and wound healing.
research Genomic and Transcriptomic Characterization of Atypical Recurrent Flank Alopecia in the Cesky Fousek
The study found that the hair loss condition in Cesky Fousek dogs is influenced by multiple genes affecting skin and muscle structure, fat metabolism, and immunity.
research Examining the Effect of Notocactus Ottonis Cold Vacuum Isolated Plant Cell Extract on Hair Growth in C57BL/6 Mice
Cactus extract from Notocactus ottonis may help promote hair growth.
research New Intranasal and Injectable Gene Therapy for Healthy Life Extension
Gene therapy in mice increased lifespan and improved health without causing cancer.
research ESGCT and FSGT Collaborative Congress Helsinki, Finland September 17–20, 2015 Abstracts
The congress highlighted new gene therapy techniques and cell transplantation methods for treating diseases.
research Differential Expression Analysis of Balding and Nonbalding Dermal Papilla MicroRNAs in Male Pattern Baldness Using a MicroRNA Amplification Profiling Method
Certain microRNAs are more common in balding areas and might be involved in male pattern baldness.
research Industry Update: The Latest Developments in the Field of Therapeutic Delivery, July 2018
New partnerships, clinical trials, and drug approvals marked progress in therapeutic delivery in July 2018.
research Why Are Men With Premature Alopecia at Higher Risk of Benign Prostatic Hyperplasia? And What About Prostate Cancer?
Men with early hair loss may have a higher risk of enlarged prostate and possibly prostate cancer due to shared hormonal factors.
research Are Sex Hormones Promising Candidates to Explain Sex Disparities in the COVID-19 Pandemic?
Sex hormones like estrogen and testosterone may affect COVID-19 severity differently in men and women, potentially influencing prevention and treatment strategies.
research Repurposing of Drugs as Novel Influenza Inhibitors from Clinical Gene Expression Infection Signatures
Existing drugs, including a blood pressure medication, show promise as new treatments for influenza.
research Transcriptome Profiling of Whisker Follicles in Methamphetamine Self-Administered Rats
Methamphetamine affects gene expression in rat whisker follicles, with key genes linked to addiction.
research Prioritizing Susceptibility Genes for the Prognosis of Male-Pattern Baldness with Transcriptome-Wide Association Study
The research identified genes linked to male-pattern baldness and potential drug targets for treatment.
research Role of Regeneration in Tissue Repairing and Therapies
The review concludes that innovations in regenerative medicine, tissue engineering, and developmental biology are essential for effective tissue repair and organ transplants.
research High-Throughput Screening for Discovering Small Molecules Capable of Increasing the Wnt/β-Catenin Signaling Pathway to Promote Hair and Nail Growth
Aminoacridine and Minoxidil together show promise for better hair and nail growth.
research Matrisomal Components Involved in Regenerative Wound Healing in Axolotl and Acomys: Implications for Biomaterial Development
Certain genes are more active during wound healing in axolotl and Acomys, which could help develop materials that improve human wound healing and regeneration.
research Neural, Adipocyte and Hepatic Differentiation Potential of Primary and Secondary Hair Folicle Stem Cells Isolated from Arbas Cashmere Goats
Hair follicle stem cells from Arbas Cashmere goats can become fat, nerve, and liver cells.
research High-Throughput Screening of 3D Co-Culture Hair Follicle Mimetic Tissue with Enhanced ECM for the Screening of Hair Growth Promoting Compounds
The new 3D system helps test hair growth treatments effectively.
research Comprehensive Transcriptome Data to Identify Downstream Genes of Testosterone Signaling in Dermal Papilla Cells
The research identified genes and non-coding RNAs in cells that could be affected by testosterone, which may help understand hair loss and prostate cancer.