TLDR The GG genotype of the KRT71 gene leads to longer wool in Gansu alpine fine-wool sheep.
The study on 315 Gansu alpine fine-wool sheep examined the polymorphism of the KRT71 gene and its impact on wool properties. Researchers identified two SNPs, SNP1 and SNP2, in the KRT71 gene, with the GG genotype associated with significantly longer mean staple length (MSL) of wool compared to other genotypes. The KRT71 protein showed strong expression in the inner root sheath, suggesting its role in hair follicle development and wool growth. These findings highlight the potential of KRT71 gene polymorphisms in enhancing wool production traits, with implications for breeding programs aimed at improving wool quality. Further research with larger sample sizes is recommended.
January 2025 in “BMC Genomics” Long non-coding RNAs help regulate wool fineness in Gansu alpine fine-wool sheep.
1 citations,
August 2024 in “Animals” KRT85 gene variations can help improve wool traits in sheep through selective breeding.
98 citations,
May 2016 in “Genes” Understanding wool keratin-associated proteins in sheep can help improve wool quality through selective breeding.
186 citations,
December 2012 in “Current opinion in cell biology” Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
1113 citations,
August 1999 in “The New England Journal of Medicine” Hair follicle biology advancements may lead to better hair growth disorder treatments.
27 citations,
November 2007 in “Genomics” Mutations in specific keratin genes cause improper hair structure in mice due to faulty keratin protein assembly.
October 2024 in “Cosmetics” Afro-textured hair needs personalized care due to its unique genetic traits.
11 citations,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
October 2024 in “Frontiers in Veterinary Science” FKBP10 and FBN2 are key proteins for hair growth in cashmere goats.
47 citations,
January 2013 in “International Journal of Cosmetic Science” Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.