June 2023 in “International journal of molecular sciences” Heat stress changes goats' skin and hair at the microscopic level and affects their genes and skin bacteria.
31 citations,
November 2015 in “PloS one” Reducing Tyrosinase prevents mature color pigment cells from forming in mouse hair.
29 citations,
November 2022 in “Nature Medicine” Genetic variations greatly affect individual metabolism and can impact health and disease risk.
11 citations,
July 2022 in “Frontiers in Immunology” Four specific genes are linked to keloid formation and could be potential treatment targets.
3 citations,
January 2021 in “Molecular genetics & genomic medicine” The study found two new mutations in a Chinese patient with severe biotinidase deficiency.
2 citations,
June 2022 in “International Journal of Molecular Sciences” Lower levels of certain genes in hair cells improve hair loss treatment outcomes.
May 2024 in “Cell proliferation” Melatonin helps hair grow by activating a specific signaling pathway.
February 2024 in “Advanced Science” The new scaffold with two growth factors speeds up skin healing and reduces scarring.
December 2023 in “International Journal of Molecular Sciences” Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.
November 2023 in “Translational Medicine Communications” Derinat may improve hair growth and quality of life in hair loss patients by reducing oxidative stress.
August 2023 in “Drug Design Development and Therapy” Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.
5 citations,
April 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” A new therapy for a skin blistering condition has not been developed yet.
5 citations,
December 2021 in “Journal of Investigative Dermatology” Hedgehog signaling in certain cells is crucial for hair growth during wound healing.
June 2024 in “Skin Research and Technology” hsa-miR-193a-5p may help diagnose and treat alopecia areata.
April 2024 in “Frontiers in endocrinology (Lausanne)” Melatonin improved secondary hair growth in goats but didn't affect primary hair density or litter size.
12 citations,
November 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” Laminin 332 is essential for normal skin cell behavior and structure.
9 citations,
August 2021 in “International journal of molecular sciences” PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.
9 citations,
May 2021 in “Frontiers in Cell and Developmental Biology” DNA methylation changes in women with PCOS could be used as disease markers and suggest new treatment targets.
13 citations,
April 2018 in “Scientific Reports” The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.
1 citations,
October 2023 in “Frontiers in Oncology” Genomic profiling for myeloid cancers can find important inherited mutations, but it's challenging when these mutations aren't related to the patient's symptoms.
April 2024 in “Human genomics” Identified genes linked to male-pattern baldness may help develop new treatments.
September 2020 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Lymphatic vessels and hair follicles interact and may influence hair growth.
8 citations,
October 2021 in “Microbiology spectrum” Researchers identified five new potential targets for leishmaniasis treatment, suggesting repurposing existing drugs could be effective.
3 citations,
April 2023 in “Veterinary sciences” Researchers found genes that may explain why some pigs grow winter hair, which could help breed cold-resistant pigs.
3 citations,
August 2022 in “Molecules/Molecules online/Molecules annual” A new strain of bacteria from the human skin can help prevent hair loss.
1 citations,
December 2022 in “Current Issues in Molecular Biology” Annurca apple extract improved hair growth in mice and could potentially prevent hair loss.
Meis2 is essential for touch sensation and proper nerve connection to touch receptors in certain skin areas of mice.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Removing UBE2N from skin cells causes inflammation and immune response, which can be lessened with specific inhibitors.
February 2023 in “Laboratory Animal Research” Cudrania tricuspidata and Sargassum fusiforme extracts improved hair growth in mice by affecting growth-related genes.
82 citations,
July 2012 in “Brain pathology” High LGR5 levels in glioblastoma indicate poor prognosis and are essential for cancer stem cell survival.