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Keratin-based hydrogels from human hair and wool are promising for wound dressings and are more eco-friendly.

This study developed a biobased copolymer called SELP::KP, showing improved hair strength, elasticity, and conditioning properties while being a safer alternative to conventional chemical treatments, based on application to human hair in a laboratory setting.

In this study, the researchers found that a keratin hydrogel filler in nerve conduits led to earlier Schwann cell migration and improved cellular behaviors compared to other fillers in a rat sciatic nerve model.

In this study, researchers modified an acellular scaffold with different concentrations of eggshell membrane protein, finding that a 5% concentration effectively enhanced tissue regeneration in mice with excisional wounds, achieving complete healing within 14 days without causing immunogenicity or inflammation.

This study aimed to enhance the skin penetration of minoxidil by encapsulating it in glycerosomal vesicles, offering a potential improvement in transdermal drug delivery for treating androgenetic alopecia. Results of the investigation were not reported.

In this study, a hydrogel with anti-inflammatory, antibacterial, antioxidant, and wound tissue adhesion properties was developed, showing significant potential for wound healing and suggesting it could offer a new and effective treatment option in clinical settings.

In this study, cinnamic acid in solution form showed strong antifungal activity against Microsporum canis, but when incorporated into hydrogels, the acid's diffusion and resulting antifungal performance decreased, though it maintained effectiveness for potential prolonged exposure.

In AGA animal models, this study found that finasteride-loaded microspheres provided rapid and sustained dihydrotestosterone suppression, promoting hair regrowth through dual-phase drug release.

This study found that novel RNA aptamers specifically inhibited FGF5-induced cell proliferation, suggesting their potential as candidates for treating FGF5-related diseases or hair disorders.

This study found that Pomiferin demonstrated potent stimulation of extracellular matrix proteins in human dermal fibroblasts and hair follicles, suggesting its potential as an ingredient in skin and scalp treatments.

This study found that PGF2alpha analogues and PGE2 stimulated hair follicle activity in mice, with PGF2alpha analogues also linked to potential side effects like poliosis when used as eye treatments.

This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.

This case report discusses the use of a prostaglandin analogue for treating eyebrow loss in a patient with frontal fibrosing alopecia, but provides no new clinical results.

This study found that topical minoxidil 5% foam was effective in promoting hair growth in both the frontal and vertex scalp for men with androgenetic alopecia.

This study found that applying Laponite clay gels to skin wounds in mice did not speed up wound closure but significantly improved healing quality compared to phosphate-buffered saline or alginate treatments, with benefits such as enhanced re-epithelialization and hair follicle stimulation near wounds.

In this study, microneedle-assisted human basic fibroblast growth factor therapy was reported to significantly improve hair regeneration in both male and female patients with androgenetic alopecia, alopecia areata, and telogen effluvium, showing greater effectiveness in males.

The hydrogel helps heal seawater-immersed wounds by reducing infection and inflammation.

In this study, both 5% minoxidil foam and 5% minoxidil liquid solution effectively improved hair diameter and density in male patients with androgenetic alopecia over 12 weeks, with the foam formulation showing a slight advantage in patient satisfaction and hair density gain.

This study presents a composite hydrogel dressing with berberine-loaded silk fibroin microspheres and Calotropis gigantea fibers that demonstrates effective antibacterial properties, enhanced mechanical strength, and promotes wound healing.

This study found that topical EGF-liposomal solution may protect hair follicles from chemotherapy-induced damage by inducing a catagen-like stage in a mouse model.

This preclinical study reported that the mix of biomimetic peptides, MGF, promoted hair growth and increased cell proliferation in cultured human hair follicles from AGA subjects.

This study developed a co-design framework using finite element analysis to optimize bubble microneedles, achieving controlled tip separation and effective drug delivery through the skin and mucosa while maintaining insertion strength.

This study found that adding topical eflornithine to hair laser treatment significantly reduced hair counts and inflammatory papules more effectively than laser therapy alone in treating pseudofolliculitis barbae.

The study reported that a poly herbal gel containing Lagenaria siceraria, Trichosanthis cucumarina, and Tridax procumbens promoted hair growth in human volunteers, with noticeable effects observed after 90 days.

This research observed that finasteride-loaded ethosomes showed improved permeation across rat skin and human cadaver scalp skin compared to unencapsulated finasteride, potentially enhancing delivery to hair follicle units.

In this study, researchers developed a new method called Enriched-GF, which enhances growth factor recovery from platelet concentrates through a combination of glass bead activation, freeze-thaw cycling, and calcium stimulation, outperforming conventional methods by providing higher and more consistent yields for regenerative medicine applications.

This research outlines the potential of nanoemulgels as a superior alternative to conventional topical treatments, noting their ability to improve skin permeability, drug release, and therapeutic targeting, though challenges remain in formulation stability and consistency.

This review discusses the potential of Pluronic F127-derived hydrogels for wound healing, examining their applications in various wound types and exploring underlying mechanisms and their interaction within the wound microenvironment.

This study found that a hydrogel containing icariin enhanced wound healing and hair-follicle regeneration in vivo by promoting M2 macrophage polarization and modulating the BMP pathway, with treated skin defects showing improved recovery and new hair follicle development compared to untreated defects.

This study found that combining basic fibroblast growth factor with minoxidil improved hair treatment efficiency and patient satisfaction compared to minoxidil alone for early-stage androgenetic alopecia in men.