research A Novel Splice Site Mutation in LIPH Identified in a Japanese Patient with Autosomal Recessive Woolly Hair
Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.
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research The Endocannabinoid Tone Regulates Human Sebocyte Biology
The endocannabinoid system affects oil production and inflammation in skin cells.
research An Underlying Mechanism of Hair Loss in Acrodermatitis Enteropathica
Zinc deficiency disrupts hair growth and cycle, but zinc supplements can fix this.
research MicroRNAs and Their Regulatory Interactions in the Human Hair Follicle
The research found that certain microRNAs are important for human hair growth and health.
research Betaine Supplementation Is Less Effective Than Methionine Restriction in Correcting Phenotypes of CBS Deficient Mice
Methionine restriction works better than betaine for treating CBS deficiency symptoms in mice.
research Epidemiology and Management of Acne in Adult Women
Many adult women suffer from persistent or late-onset acne, and while various treatments exist, finding the right one can be challenging.
research Sterol Intermediates of Cholesterol Biosynthesis Inhibit Hair Growth and Trigger an Innate Immune Response in Cicatricial Alopecia
Cholesterol-related compounds can stop hair growth and cause inflammation in a type of scarring hair loss.
research PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds
Certain natural and synthetic compounds may help treat inflammatory skin diseases by targeting a specific signaling pathway.
research Acne and Systemic Disease
Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
research Role of FGFR2-Signaling in the Pathogenesis of Acne
Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.
research Genetically Modified Laboratory Mice with Sebaceous Glands Abnormalities
Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.
research Pinus Thunbergii Bark Extract Rich in Flavonoids Promotes Hair Growth in Dorsal Skin by Regulating Inflammatory Cytokines and Increasing Growth Factors in Mice
Pine bark extract helps mice grow hair by reducing inflammation and boosting growth factors.
research Scd1 ab-Xyk: A New Asebic Allele Characterized by a CCC Trinucleotide Insertion in Exon 5 of the Stearoyl-CoA Desaturase 1 Gene in Mouse
A new mouse mutation causes skin and hair defects due to a gene change.
research Cicatricial Alopecia: What's New in Etiology?
Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.
research Anti-Amnesia-Like Effect of Pinus Densiflora Extract by Improving Apoptosis and Neuroinflammation in Trimethyltin-Induced ICR Mice
Pinus densiflora extract may help improve memory and reduce brain inflammation.
research Dissecting Fibroblast Heterogeneity in Health and Fibrotic Disease
Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
research The Postnatal Offspring of Finasteride-Treated Male Rats Shows Hyperglycemia, Elevated Hepatic Glycogen Storage, and Altered GLUT2, IR, and AR Expression in the Liver
Finasteride-treated male rats' offspring had altered glucose metabolism, potentially increasing diabetes risk.
research Role of Metformin in Polycystic Ovary Syndrome (PCOS): Related Infertility
Metformin helps reduce PCOS-related infertility by improving insulin sensitivity and inducing ovulation.
research Role of Insulin, Insulin-Like Growth Factor-1, Hyperglycemic Food, and Milk Consumption in the Pathogenesis of Acne Vulgaris
Eating high-glycemic foods and drinking milk may worsen acne by increasing insulin and IGF-1 levels.
research Distinctive Acne Entities
Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.
research Genetic Ablation of Myelin Protein Zero-Like 3 in Mice Increases Energy Expenditure, Improves Glycemic Control, and Reduces Hepatic Lipid Synthesis
Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
research Inhibition of Rat 5α-Reductase Activity and Testosterone-Induced Sebum Synthesis in Hamster Sebocytes by an Extract of Quercus Acutissima Cortex
An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
research Adipokines in the Skin and Dermatological Diseases
Adipokines affect skin health and could be targeted for treating skin diseases.
research Effect of Ficus Carica Leaf Extract on the Gene Expression of Selected Factors in HaCaT Cells
Ficus carica leaf extract may help treat skin disorders by reducing inflammation and androgen effects in skin cells.
research Effect of Dihydrotestosterone on the Upregulation of Inflammatory Cytokines in Cultured Sebocytes
Dihydrotestosterone increases certain inflammatory signals in skin cells, potentially contributing to acne.
research Global Single-Cell Sequencing Landscape of Adipose Tissue of Different Anatomical Site Origin in Humans
Different parts of the body's fat tissue have unique cell types and characteristics, which could help treat chronic wounds.
research Cannabinoid Compounds as a Pharmacotherapeutic Option for the Treatment of Non-Cancer Skin Diseases
Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.
research Hair in Health and Disease: An Introduction
Hair health depends on various factors and hair loss can significantly affect a person's well-being; understanding hair biology is key for creating effective hair care treatments.
research Dermal White Adipose Tissue: A New Component of the Thermogenic Response
Skin fat helps with body temperature control and has other active roles in health.
research The 'Bald' Phenotype (Androgenetic Alopecia) Is Caused by the High Glycemic, High Cholesterol, and Low Mineral 'Western Diet'
Western diet may cause male pattern baldness; low glycemic diet with magnesium could help.