82 citations,
May 2009 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Caffeine penetrates human skin in lab tests similarly to real-life conditions, but actual skin use is still essential for accurate results.
72 citations,
June 2001 in “Journal of Investigative Dermatology” S100A4 and S100A6 proteins may activate stem cells for hair follicle regeneration and could be potential targets for hair loss treatments.
62 citations,
December 2013 in “Aaps Journal” Squarticles effectively deliver hair growth drugs to follicles and dermal papilla cells.
62 citations,
October 2010 in “Journal of biomedical nanotechnology” Nanoparticles can enter the skin, potentially causing toxicity, especially in damaged skin.
62 citations,
May 1997 in “Journal of Pharmaceutical Sciences” Sebaceous glands in the skin play a key role in absorbing the antiandrogen drug RU 58841, especially when it's encapsulated in liposomes.
55 citations,
June 2013 in “Dermatologic Surgery” Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.
39 citations,
February 2014 in “European journal of pharmaceutics and biopharmaceutics” Massage increases how deep both rigid and flexible liposomes can go into skin, with flexible ones going deeper, and covering the skin (occlusion) helps rigid ones more.
34 citations,
October 1994 in “Journal of Pharmaceutical Sciences” Ethanol over 50% helps minoxidil absorb better into skin.
33 citations,
October 2016 in “European Journal of Pharmaceutical Sciences” Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.
27 citations,
September 2018 in “Medicines” Oleic acid nanovesicles improve minoxidil absorption in hair follicles for alopecia treatment.
26 citations,
May 2012 in “Pharmaceutical Development and Technology” PEVs effectively deliver minoxidil through skin.
23 citations,
June 2014 in “Journal of Pharmaceutical Sciences” Finasteride cream helps hair growth with less side effects.
20 citations,
July 2015 in “Journal der Deutschen Dermatologischen Gesellschaft” Green tea may help with skin health and protect against UV damage, but more research is needed to confirm its safety and effectiveness.
19 citations,
July 2020 in “Journal of drug delivery science and technology” Nanoemulsions with minoxidil and clove oil effectively target hair follicles for better alopecia treatment.
18 citations,
April 2022 in “Frontiers in bioengineering and biotechnology” Gelatin microspheres with stem cells speed up healing in diabetic wounds.
16 citations,
March 2008 in “International journal of pharmaceutics” Different factors like pH, gel type, and chemical enhancers affect how well hydrocortisone gets into hair follicles, and less hydrated skin doesn't work well with the test method.
15 citations,
October 2020 in “European journal of pharmaceutics and biopharmaceutics” Caffeine penetrates skin quickly through open hair follicles, but less through closed ones, with levels becoming equal after 22 hours.
15 citations,
August 2013 in “Stem Cells and Development” The method increases stem-like cells for better skin regeneration.
12 citations,
March 2020 in “Journal of Bioactive and Compatible Polymers” Nanoparticles show potential for controlled release of hair loss drugs, improving treatment effectiveness.
9 citations,
June 2021 in “International Journal of Pharmaceutics” Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.
9 citations,
August 2014 in “European journal of ophthalmology” PGF2α receptors in human eyelids are found in specific parts of hair follicles, explaining eyelash changes with glaucoma treatment.
3 citations,
January 2012 in “Elsevier eBooks” The document says that there are treatments for hair and nail diseases.
3 citations,
September 1989 in “Journal of Investigative Dermatology” Methyl caprate greatly increases drug absorption through the skin and is better than other enhancers.
1 citations,
June 2007 in “Almustansiriya journal of pharmaceutical sciences/Al-Mustansiriyah journal of pharmaceutical sciences” Cimetidine cream shows potential for treating warts and female-pattern hair loss.
April 2019 in “Journal of Investigative Dermatology” Caffeine can protect scalp hair follicles from damage caused by UV radiation.
October 2020 in “Journal of Pharmaceutical Sciences” Topical finasteride with EGCG or TA improves drug release and dermal uptake, potentially treating hair loss effectively.
13 citations,
November 2017 in “BMC Veterinary Research” Fusidic acid can be an effective topical treatment for superficial bacterial infections in dogs.
1 citations,
April 2021 in “Clinical, Cosmetic and Investigational Dermatology” Conflicting findings in androgenic alopecia are likely due to biopsy location, hair diameter diversity, and hair follicle miniaturization.
79 citations,
December 2017 in “Cosmetics” Effective sunscreen formulations can reduce skin absorption and enhance protection.
71 citations,
February 2012 in “The American Journal of Human Genetics” A specific ATR gene mutation is linked to a hereditary oropharyngeal cancer syndrome.