Conflicting Reports Regarding the Histopathological Features of Androgenic Alopecia: Are Biopsy Location, Hair Diameter Diversity, and Relative Hair Follicle Miniaturization Partly to Blame?

April 2021 in “ Clinical, Cosmetic and Investigational Dermatology ”

Robert S. English, Sophia Ruiz

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research The Role of Prostaglandins in Androgenetic Alopecia

4 citations , February 2021 in “International Journal of Dermatology”

Prostaglandins may contribute to male hair loss; targeting them could help treat it.

research Quantitative Analysis of the Anatomical Changes in the Scalp and Hair Follicles in Androgenetic Alopecia Using Magnetic Resonance Imaging

2 citations , January 2021 in “Skin Research and Technology”

MRI reveals thinner scalps and smaller hair follicles in people with androgenetic alopecia.

research Response to Letter to the Editor on Inflammation in Androgenetic Alopecia

1 citations , May 2020 in “Journal of The American Academy of Dermatology”

Inflammation and fibrosis are important factors in hair loss, but more research with better control samples is needed.

research Reply to Comment on: Pattern Hair Loss. Assessment of Inflammation and Fibrosis on Histologic Sections

1 citations , May 2020 in “Journal of The American Academy of Dermatology”

The authors agree more research with proper control groups is needed to understand hair loss.

research Pattern Hair Loss: Assessment of Inflammation and Fibrosis on Histologic Sections

7 citations , March 2020 in “Journal of The American Academy of Dermatology”

Inflammation and fibrosis are not significantly different in pattern hair loss compared to controls.

research Evaluation of Hair Density and Hair Diameter in the Adult Thai Population Using Quantitative Trichoscopic Analysis

31 citations , February 2020 in “BioMed Research International”

Thai people's hair density decreases with age and varies by scalp area, but hair thickness stays the same regardless of age or scalp area.

research Correlation Between Clinical Features, Biochemical Parameters, and Histopathological Findings in Women with Patterned Baldness: A Study from North India

4 citations , May 2019 in “PubMed”

Patterned hair loss in women is linked to hormonal imbalances and biochemical changes, and should be evaluated for underlying health issues.

research Prostaglandins in Androgenetic Alopecia in 12 Men and Four Women

8 citations , May 2019 in “Journal of The European Academy of Dermatology and Venereology”

research A Study of the Histopathological Features of Alopecias on Transverse Sections of Scalp Biopsies

3 citations , January 2019 in “Indian Journal of Dermatology”

Transverse scalp biopsy sections help diagnose different alopecias by showing hair follicle details and inflammation patterns.

research Non-Scarring Alopecias in Iranian Patients: A Histopathological Study With Hair Counts

2 citations , January 2018 in “DOAJ (DOAJ: Directory of Open Access Journals)”

The most effective way to diagnose non-scarring hair loss is by transverse sectioning, and some cases, particularly in males with inflammation around hair follicles, might be curable.

research Hair Diameter Variation in Different Vertical Regions of the Occipital Safe Donor Area

10 citations , July 2017 in “Archives of Plastic Surgery”

Hair thickness decreases from the upper to lower areas of the back of the head, affecting hair transplant results.

research Prostaglandin D2 Inhibits Hair Growth and Is Elevated in Bald Scalp of Men with Androgenetic Alopecia

205 citations , March 2012 in “Science Translational Medicine”

PGD2 stops hair growth and is higher in bald men with AGA.

research Histopathology of Alopecia: A Clinicopathological Approach to Diagnosis

170 citations , January 2010 in “Histopathology”

The conclusion is that accurate diagnosis of different types of hair loss requires good teamwork between skin doctors and lab experts.

research Androgenetic Alopecia in Males: A Histopathological and Ultrastructural Study

42 citations , June 2009 in “Journal of Cosmetic Dermatology”

Hair loss in males involves inflammation, collagen buildup, and follicle damage, with severity increasing with age and baldness duration.

research Dermal Fibrosis in Male Pattern Hair Loss: A Suggestive Implication of Mast Cells

19 citations , February 2008 in “Archives of Dermatological Research”

Mast cells might contribute to hair loss by causing skin thickening.

research Anisotrichosis: A Novel Term to Describe Pattern Alopecia

25 citations , May 2007 in “Journal of The American Academy of Dermatology”

The document suggests "anisotrichosis" as a new term for hair thickness variation in common baldness.

research Histological Features of Peripilar Signs Associated with Androgenetic Alopecia

95 citations , January 2004 in “Archives of Dermatological Research”

Peripilar signs can help diagnose androgenetic alopecia and reveal its cause.

research Transplants from Balding and Hairy Androgenetic Alopecia Scalp Regrow Hair Comparably Well on Immunodeficient Mice

17 citations , May 2003 in “Journal of The American Academy of Dermatology”

Hair from balding and non-balding areas regrows similarly on mice.

research Hair Diameter Diversity: A Clinical Sign Reflecting Follicle Miniaturization

41 citations , May 2001 in “PubMed”

Different thicknesses of hair strands can indicate the severity of hair thinning.

research The psychosocial consequences of androgenetic alopecia: a review of the research literature

180 citations , September 1999 in “British Journal of Dermatology”

Hair loss affects self-esteem and quality of life; treatments can help.

research Chronic telogen effluvium: Increased scalp hair shedding in middle-aged women

234 citations , December 1996 in “Journal of The American Academy of Dermatology”

Middle-aged women with chronic telogen effluvium experience increased hair shedding but usually don't get significantly thinner hair.

research Quantification of hair follicle parameters using computer image analysis: A comparison of androgenetic alopecia with normal scalp biopsies

13 citations , August 1995 in “Australasian Journal of Dermatology”

Hair follicles are smaller in people with androgenetic alopecia compared to those with normal scalps.

research Diagnostic and predictive value of horizontal sections of scalp biopsy specimens in male pattern androgenetic alopecia

309 citations , May 1993 in “Journal of The American Academy of Dermatology”

Horizontal scalp biopsy sections effectively diagnose and predict MPAA, with follicular density and inflammation impacting hair regrowth.

research The Transverse Anatomy of Androgenic Alopecia

42 citations , December 1990 in “The Journal of Dermatologic Surgery and Oncology”

The study found that horizontal sections of scalp biopsies are better for analyzing hair loss, showing fewer hairs and more fine hairs in balding areas.

research Histologic Response to Topically Applied Minoxidil in Male-Pattern Alopecia

38 citations , October 1988 in “Clinics in Dermatology”

Minoxidil can help grow hair and make hair follicles bigger, but it can also cause side effects.

research Male Pattern Alopecia A Histopathologic and Histochemical Study

94 citations , August 1975 in “Journal of Cutaneous Pathology”

Male pattern baldness involves smaller hair follicles, larger oil glands, and other tissue changes, but not major blood supply issues.