Quantification of Hair Follicle Parameters Using Computer Image Analysis: A Comparison of Androgenetic Alopecia with Normal Scalp Biopsies

This study from 27 years ago used computer image analysis to compare hair follicle parameters in individuals with androgenetic alopecia (AGA) and those with normal scalp biopsies. The study found that hair follicle diameters were smaller in individuals with AGA, and vellus hair follicles were significantly smaller than terminal hair follicles. The study also found that the outer root sheath areas and hair shaft diameters were smaller in individuals with AGA compared to those with normal scalp biopsies. The study suggests that computer image analysis can be a useful tool for objectively assessing hair regrowth in individuals with AGA and can be adapted for use in clinical trials determining the efficacy of hair growth promoters.