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Phospholipase Cδ1 is crucial for normal skin and hair development.

This narrative review explores gender differences in the epidemiology, risk factors, and effects of COVID-19, emphasizing the need for further analysis using comprehensive gender indicators to shape effective public health strategies and policies.

This study found that the E3 ligases NEDD4 and NEDD4L regulate intestinal stem cell priming by degrading the LGR5 receptor, and their loss leads to increased Wnt activation and crypt proliferation, which in turn accelerates intestinal tumor progression in mice.

This study identified gene expression differences between dermal papilla cells from primary and secondary hair follicles in Cashmere goats, highlighting their roles in hair follicle morphogenesis.

This study found that BMP-2 activates Dlx3 gene transcription in murine keratinocytes by binding with Smad1/Smad4, suggesting a mechanism for BMP signaling's role in skin and hair follicle regulation.

This review discusses the free hormone hypothesis for measuring "free" testosterone and critiques its theoretical basis and clinical application, noting it lacks critical empirical testing and has inconsistent utility in assessing androgen status.

This study suggests that the structural integrity and physical proximity of Whn's DNA binding and activation domains are crucial for hair keratin gene activation and may explain the nude phenotype.

This study identified altered expression of MMP-19 in the skin's epidermal layers during diseases like psoriasis and eczema, implying a role in disease processes.

This study reports that LL-37 treatment enhances cell proliferation, migration, and secretion of regenerative factors in adipose-derived stem cells, potentially promoting hair growth in vivo.

This review discusses neuroimmune communication in skin disorders and peripheral neuropathic pain, highlighting the complex interactions between sensory neurons and immune cells; it reports no new clinical results but suggests potential future therapies.

This study found that the hHa7 gene in hair follicle trichocytes is the first identified to have its expression directly regulated by androgens, suggesting it as a marker for androgen action on hair follicles.

This study demonstrated that hair follicle bulge stem cells can form epidermis in a tissue-engineered skin model, highlighting the significance of K5/K17 filaments in slow-cycling stem cell subsets.

This review discusses the role of toll-like receptors in cancer treatment, providing an overview of pre-clinical studies and clinical trials on TLR-targeted therapies and noting the challenges and future prospects.

This review discusses the molecular and functional aspects of the nude gene in skin biology, providing insights into its role and evolutionary development, but reports no new results.

This review found significant progress in 3D bioprinting for surgery, noting advances in creating complex tissue constructs, while highlighting ongoing challenges like vascularization and integration with host tissue, emphasizing the need for further research and regulatory development.

This review discusses the unique pharmacokinetic limitations of terbinafine in children with tinea capitis and reports no new clinical results, highlighting the need for consideration of these factors in future studies.

This study found that vitamin D receptor activation in primary keratinocytes can occur independently of the 1,25-dihydroxyvitamin D₃ ligand, likely through interaction with retinoid X receptors.

This study found that the HS III element in the K14 gene's regulatory sequence promotes gene expression in inner root sheath keratinocytes, highlighting cooperative interactions in keratinocyte-specific gene regulation.

This study identified a target relationship between miR-148a, miR-10a, and BMP7, suggesting these microRNAs influence dermal papilla cell proliferation and may regulate hair follicle growth.

This review explores current and emerging treatments for polycystic ovary syndrome, focusing on managing hyperandrogenism and cardiometabolic risk, but reports no new clinical results.

This study found that Frizzled genes Fzd3 and Fzd6 are redundantly involved in controlling hair follicle polarity in mice, but operate through distinct mechanisms, highlighting their complex role in hair orientation.

This study found that adipose-derived stem cells from HIV-infected patients with lipodystrophy associated with HAART demonstrated similar growth and differentiation potential as those from HIV-uninfected patients, suggesting potential for autologous regenerative therapy.

This study found that the binding and release of BMP-2 from kerateine biomaterials are significantly influenced by pH and salt concentration, highlighting the potential for developing improved bone repair systems.

This review discusses three classes of thiazole-bearing compounds in drug development and presents preclinical findings but reports no new experimental results, highlighting the need for further drug discovery.

This review discusses the role of jasmonic acid and its conjugates in enhancing plant stress tolerance and balancing growth and defense mechanisms but provides no new experimental data.

This analysis reports that hepatitis B surface protein antigen exposure is associated with an increased risk of alopecia areata.

This study developed an efficient method for isolating and enriching multipotent ovine hair follicle stem cells, which may aid in research on the ovine hair cycle and future wool production.

This review discusses methods for generating induced pluripotent stem cells and highlights their recent applications in studying and treating COVID-19, but it reports no new experimental results.

This study found that local platelet-rich plasma injection improved mid-term outcomes for carpal tunnel syndrome more effectively than other conservative treatments, although long-term effects and standardization need further research.

This study demonstrated that genetically engineered stem cells from human hair follicles can reverse hyperglycemia and reduce mortality in mice with type 1 diabetes by overexpressing the human insulin gene.