Evaluation of the Relationship Between Alopecia Areata and Viral Antigen Exposure

August 2017 in “ American journal of clinical dermatology ”

Christopher T. Richardson, Matthew S. Hayden, Elaine S. Gilmore, Brian Poligone

alopecia areata hepatitis B virus HBV interferon-beta IFN-β SLC45A2 MHC AA

Studysummary This analysis reports that hepatitis B surface protein antigen exposure is associated with an increased risk of alopecia areata.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer

View this study on link.springer.com →

Discuss this study in the Community →

Research cited in this study

12 / 12 results

research Treatment of an Alopecia Areata Patient with Tofacitinib Results in Regrowth of Hair and Changes in Serum and Skin Biomarkers

70 citations , April 2016 in “Experimental Dermatology”

In this study, oral tofacitinib treatment led to significant hair regrowth and changes in skin and blood biomarkers in a patient with alopecia areata.

research Rapid Skin Repigmentation on Oral Ruxolitinib in a Patient with Coexistent Vitiligo and Alopecia Areata

157 citations , December 2015 in “Journal of the American Academy of Dermatology”

This case study reported significant but temporary hair regrowth and skin repigmentation in a patient with vitiligo and alopecia areata during treatment with oral ruxolitinib.

research Alopecia Areata Profiling Shows TH1, TH2, and IL-23 Cytokine Activation Without Parallel TH17/TH22 Skewing

176 citations , August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology”

This study identified a distinct cytokine activation signature in alopecia areata, involving TH2, TH1, IL-23, and IL-9/TH9 pathways, suggesting potential targeting strategies similar to those in psoriasis and atopic dermatitis.

research Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib

184 citations , February 2015 in “EBioMedicine”

This study observed that baricitinib treatment led to significant improvement in a patient's alopecia areata symptoms and suggests further clinical trials to explore its potential as a treatment.

research Alopecia Areata Is Driven by Cytotoxic T Lymphocytes and Is Reversed by JAK Inhibition

701 citations , August 2014 in “Nature medicine”

This study found that JAK inhibitors promote hair regrowth in both mice and human alopecia areata cases by blocking key immune pathways involved in disease development.

research Killing Two Birds with One Stone: Oral Tofacitinib Reverses Alopecia Universalis in a Patient with Plaque Psoriasis

185 citations , June 2014 in “Journal of Investigative Dermatology”

This case report describes complete hair regrowth in a patient with alopecia universalis and improved psoriasis after treatment with the oral Janus kinase inhibitor, tofacitinib.

research Alopecia Areata: An Autoimmune Disease Causing Hair Loss

421 citations , April 2012 in “The New England Journal of Medicine”

Alopecia Areata is an autoimmune condition causing hair loss with no cure and treatments that often don't work well.

research Type 1 Interferon Signature in the Scalp Lesions of Alopecia Areata

52 citations , March 2010 in “British Journal of Dermatology”

This study demonstrated the expression of type 1 interferon-related proteins in inflammatory lesions of alopecia areata, showing a distinct distribution pattern compared to cicatricial alopecia.

Lichen Planus and Other Cutaneous Manifestations in Chronic Hepatitis C: Pre- and Post-Interferon-Based Treatment Prevalence in a Cohort from a Low Hepatitis C Virus Endemic Area

research Lichen Planus and Other Cutaneous Manifestations in Chronic Hepatitis C: Pre- and Post-Interferon-Based Treatment Prevalence in a Cohort from a Low Hepatitis C Virus Endemic Area

34 citations , April 2008 in “Journal of the European Academy of Dermatology and Venereology”

This study reported that while lichen planus was not significantly linked to hepatitis C virus infection, pruritus, dry skin, and hair loss were more common in HCV patients post-interferon treatment.

Reversible Alopecia Universalis Secondary to PEG-Interferon Alpha-2b and Ribavirin Combination Therapy in a Patient with Chronic Hepatitis C Virus Infection

research Reversible Alopecia Universalis Secondary to PEG-Interferon Alpha-2b and Ribavirin Combination Therapy in a Patient with Chronic Hepatitis C Virus Infection

41 citations , August 2007 in “European Journal of Gastroenterology & Hepatology”

This case report documents a reversible instance of complete body hair loss (alopecia universalis) in a patient undergoing chronic hepatitis C treatment with pegylated interferon alpha-2b and ribavirin, with hair regrowth observed within three months after therapy completion.

research Alopecia Areata During Interferon Alpha-2b and Ribavirin Therapy

35 citations , January 2002 in “Dermatology”

This article discusses alopecia areata occurring during Interferon Alpha-2b/Ribavirin therapy and reports no new clinical results.

research Hair Loss After Routine Immunizations

87 citations , October 1997 in “JAMA”

This case series suggests a possible, though likely very rare, association between vaccinations and hair loss, calling for further research in more defined populations.