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Advanced therapies like gene, cell, and tissue engineering show promise for hair regrowth in alopecia, but their safety and effectiveness need more verification.

A substance called 15-deoxy prostaglandin J2 can cause hair follicle cells to die, which might explain how prostaglandin D2 can lead to hair loss.

Sebaceous glands are involved in various skin disorders, some treatable with medications like finasteride and minoxidil.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Decreased IGF-1R expression may contribute to sacrococcygeal pilonidal sinus development.

New skin substitutes for treating severe burns and chronic wounds are being developed, but a permanent solution for deep wounds is not yet available commercially.

Micro-CT helps identify suitable areas for surgical procedures based on blood vessel distribution in hypospadias-affected rats.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Shampoo with heat-killed Lacticaseibacillus paracasei GMNL-653 improves scalp health and hair growth by changing scalp bacteria.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Ruby laser hair removal significantly reduces hair density.

Polyurethane dressings show promise for wound healing but need improvements to adapt better to the healing process.

Testosterone may influence COVID-19 severity and outcomes.

Transplanting skin cells is a safe, effective, and affordable treatment for vitiligo.

Cell transplantation faces challenges in genitourinary reconstruction, but alternative tissue sources and microencapsulation show promise.

Different light affects cell functions and can help treat skin conditions.

Permanent hair dye mixtures can irritate and damage the skin.

The research provides a gene-based framework for hair biology, highlighting the Hippo pathway's importance and suggesting links between hair disorders, cancer pathways, and the immune system.

Cytokines are important for immune responses and treating diseases, but they can cause side effects like fever and skin issues.

Regenerative cellular therapies show promise for treating non-scarring hair loss but need more research.

Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.

Some skin conditions are associated with other serious diseases, and office microscopy may miss many fungal infections.

Research on epidermal stem cells has advanced significantly, showing promise for improved clinical therapies.

Short telomeres contribute to aging and cancer, and while telomerase can delay aging, it may also promote cancer.

Finasteride caused long-term sexual and non-sexual side effects in young men with hair loss.

Marine-derived ingredients show potential for hair health but need more human trials to confirm effectiveness.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.