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EGF and TGF-α help maintain hair cell cultures, but TGF-β1 stops their growth.

In this study, FGF12 was found to promote hair growth in mice by inducing the anagen phase of hair follicles, suggesting potential for hair loss therapy.

In this study, fisetin applied to the dorsal skin of mice activated hair follicle stem cells through exosome secretion from keratinocytes, promoting hair growth.

In this study, hair follicle germs containing vascular endothelial cells showed improved hair regeneration and morphogenesis-related gene expression in mice, suggesting a promising strategy for hair regenerative medicine.

This study found that the Chinese herb Ligustrum lucidum may enhance expression of hair growth-related genes, HGF and VEGF, in cultured mouse hair follicles.

This study found that YiFa compound medicated serum significantly promoted the proliferation of follicle stem cells and increased mRNA expression of K19 and β1 integrin in a mouse model, suggesting a potential mechanism for treating alopecia.

This study reports that EGF at specific concentrations promotes the proliferation and migration of hair follicle ORS cells by activating the Wnt/β-catenin signaling pathway in vitro.

This study found that dysregulation of the folliculin-p0071 interaction may lead to changes in cell adhesion and signaling, contributing to conditions like emphysema and renal cell carcinoma.

In this pilot study, treatment with lyophilized platelet derived growth factors showed improvement in women with androgenetic alopecia, suggesting it may be a promising new therapy.

This review discusses partial longitudinal-follicular unit transplantation (PL-FUT) for hair loss and notes its potential to multiply hair follicles while preserving donor areas, but reports no new clinical results.

This study successfully developed a method to culture human hair follicle cells without a biological feeder layer, maintaining cell differentiation for a month.

This study found that folliculin deficient renal cancer cells were more sensitive to irradiation due to increased autophagic cell death, suggesting a potentially enhanced therapeutic approach when combined with autophagy inducers like rapamycin.

This study found that organoid cultures of human epithelial and mesenchymal cells can produce hair peg-like structures, and their growth is enhanced by minoxidil, suggesting potential for hair drug screening.

In this study, oral spermidine supplementation was found to significantly prolong the hair follicle anagen phase and reduce hair loss, with effects persisting three months after treatment in healthy participants, suggesting potential therapeutic benefits for hair loss conditions.

This study found that dispersed hair follicle cells can be cultured successfully on collagen type IV, potentially offering an alternative to cultured epidermal keratinocytes for skin treatment.

In this study, estetrol (E4) treatment was associated with increased hair growth in ex vivo human hair follicles, suggesting its potential as a treatment for hair loss disorders.

This study describes a protocol for generating hair follicle germ-like organoids from human skin cells, which may aid in alopecia drug discovery and understanding hair follicle regeneration.

In this study, researchers found that FGF9 plays a significant role in sheep wool growth by accelerating the proliferation and cell cycle of dermal papilla cells, potentially through regulation of the Wnt/β-catenin signaling pathway.

This review explores the biology of wool follicles and suggests their potential use as research models in modern biology, but it reports no new findings.

This study observed that adults with thinning hair who ingested a patented botanical-based supplement experienced significant increases in hair shaft diameter and reductions in hair breakage over 180 days, suggesting improved hair strength and length across various demographic groups.

This study found that FGF18 is crucial for regulating hair follicle rest and growth phases, as its absence in mice leads to a shorter resting phase and rapid hair cycling.

This study demonstrated that a finasteride-loaded proniosome significantly enhanced transfollicular delivery and hair growth in mice without causing skin irritation, with effects comparable to a 2% minoxidil solution.

This study found that a serum-free culture system supported hair growth from follicles responsive to calcium, glucose, and amino acids, with insulin enhancing the growth, while other factors had no effect.

New treatment with Wnt proteins and growth factors safely increases hair thickness.

This review discusses the potential of the hair follicle dermis to direct hair development and explores concepts related to hair growth and androgenetic alopecia, without reporting new clinical results.

This review discusses the concept of telogen effluvium and emphasizes that its diagnosis requires detailed clinical evaluation and tests to identify underlying causes; no new clinical results are reported.

In this study, researchers established a model using Mongolia Sheep hair follicles to investigate growth mechanisms, noting that adding insulin and hydrocortisone helped maintain follicle shape during extended culture.

This study analyzed proteomic changes in Jiangnan cashmere goats' secondary hair follicles and found that the PLIN2 gene significantly impacts hair follicle growth cycles by affecting dermal papilla cell proliferation, offering insights into breeding strategies to enhance cashmere yield.

This article discusses methods to enhance finasteride delivery to scalp skin using heat and chemical penetration enhancers and reports no new experimental findings.