research Exploring the Potential of the Novel IFNγ Aptamer TAGX-0003 as a Treatment for Alopecia Areata in Pre-Clinical Models
The new aptamer TAGX-0003 shows promise as an effective treatment for hair loss disorder alopecia areata.
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research Human Regulatory Gamma Delta T Lymphocytes as Novel Autoimmunity-Protective Cells: Lessons from Alopecia Areata
γδTregs may help treat autoimmune diseases like alopecia areata by promoting hair regrowth and reducing immune attacks.
research MiR-199a-3p Regulates the PTPRF/β-Catenin Axis in Hair Follicle Development: Insights into the Pathogenic Mechanism of Alopecia Areata
miR-199a-3p controls hair growth and is linked to alopecia areata.
research Primary Cicatricial Alopecia: Diagnosis and Treatment
Primary cicatricial alopecia, a rare disorder causing permanent hair loss, is hard to diagnose and treat, with treatments like anti-inflammatory drugs and steroids offering varied results and no guaranteed cure. Psychological support for patients is important, and future research should aim to identify causes of the condition.
research Pathogenesis and Regenerative Therapy in Vitiligo and Alopecia Areata: Focus on Hair Follicle
Hair follicles are key to treating vitiligo and alopecia areata, but challenges exist.
research Regulatory T Cells in Skin Mediate Immune Privilege of the Hair Follicle Stem Cell Niche
Regulatory T cells protect hair follicle stem cells by maintaining immune privilege in the skin.
research Alopecia Areata: What’s New in Epidemiology, Pathogenesis, Diagnosis, and Therapeutic Options?
New insights into the causes and treatments for the autoimmune hair loss condition Alopecia areata have been made.
research Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata
Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
research Alopecia Areata: A Tissue-Specific Autoimmune Disease of the Hair Follicle
Alopecia areata is an autoimmune condition causing hair loss due to the immune system attacking hair follicles, often influenced by genetics and stress.
research Intralesional Steroids for Alopecia Areata
Intralesional steroids can help regrow hair in some alopecia areata patients but have side effects.
research Scratching the Surface of Skin Development
The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
research Vasoactive Intestinal Peptide, Whose Receptor-Mediated Signaling May Be Defective in Alopecia Areata, Provides Protection from Hair Follicle Immune Privilege Collapse
A substance called VIP might protect hair follicles from being attacked by the immune system, and problems with VIP signaling could lead to hair loss in alopecia areata.
research Role of Direct Immunofluorescence on Outer Root Sheath of Hair Follicle in Monitoring Disease Activity of Pemphigus Vulgaris
Testing hair roots with a special dye is a simple, non-invasive way to check disease progress in pemphigus vulgaris patients.
research Extracellular Vesicles Including Exosomes for Hair Follicle Regeneration
Extracellular vesicles, including exosomes from certain cells, can stimulate hair growth.
research Alopecia Areata: Clinical Perspective and an Insight into Pathogenesis
Alopecia areata causes hair loss due to an immune attack on hair follicles, influenced by genetics and environment.
research Endogenous Retinoids in the Pathogenesis of Alopecia Areata
Vitamin A affects hair loss and immune response in alopecia areata.
research Gradually Increased Stress Levels in the Days Leading to an Acute Myocardial Infarction Detected by a New Biomarker-Based Approach
Higher stress levels were found about two weeks before a heart attack.
research Genome-Wide Association Study in Alopecia Areata Implicates Both Innate and Adaptive Immunity
Alopecia areata involves both innate and adaptive immunity, with specific genes linked to the disease.
research Regulation and Dysregulation of Hair Regeneration: Aiming for Clinical Application
Understanding hair growth involves complex factors, and more research is needed to improve treatments for hair loss conditions.
research Alopecia Universalis in a Child with Good Response to Combination Therapy: A Case Report
A young child with complete hair loss improved significantly with a combination of hair growth treatments and laser therapy.
research Quiescent Tissue Stem Cells Evade Immune Surveillance
Inactive stem cells in hair follicles and muscles can avoid detection by the immune system.
research Immunology of the Human Nail Apparatus: The Nail Matrix Is a Site of Relative Immune Privilege
The nail matrix has a reduced immune response, protecting it from autoimmunity.
research The Effect of Ferritin, Vitamin D, and Hormonal and Biochemical Parameters on Female-Pattern Hair Loss After COVID-19 Infection
Low ferritin and Vitamin D levels may cause hair loss after COVID-19.
research Current and Future Pharmacotherapy for Alopecia Areata
New treatments for hair loss show promise but need more research to confirm safety and effectiveness.
research The PPAR-γ Modulator, N-Acetyl-GED, Protects From Epithelial-Mesenchymal Transition in Human Hair Follicles: Potential Relevance for Scarring Alopecia
N-acetyl-GED may help prevent and partially reverse a process that leads to scarring hair loss.
research Computer-Assisted Epitope Prediction Revealed Potential Autoantigens Associated with Human Alopecia Areata
Melanogenesis-related proteins may trigger immune responses in alopecia areata patients.
research LFA-1 Blockade Prevents the Onset of Alopecia Areata in C3H/HeJ Mice
Blocking LFA-1 prevents hair loss in mice.
research Hair Follicle as a Target of Stress Hormones and Autoimmune Reactions
Stress hormones and autoimmune reactions can cause hair loss.
research Targeting the Hippo/YAP/TAZ Signalling Pathway: Novel Opportunities for Therapeutic Interventions into Skin Cancers
Blocking YAP/TAZ could be a new way to treat skin cancer.
research Advances in Hair Diseases
The review highlights the importance of stem cells in hair health and suggests new treatment strategies for hair loss conditions.