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The document suggests a new model for evaluating public research that better captures the full value of knowledge creation and use, using PCOS research as an example.

Dermoscopy is an effective tool for accurately detecting skin cancers.

Fat-derived stem cells, platelet-rich plasma, and biomaterials show promise for healing chronic skin wounds and improving soft tissue with few side effects.

Nanoparticulate systems improve drug delivery by controlling release, protecting drugs, changing absorption and distribution, and concentrating drugs in targeted areas.

Microneedles are effective for painless drug delivery and promoting wound healing and tissue regeneration.

Moderately high prolactin levels do not cause hair loss in women.

Confocal Laser Scanning Microscopy (CLSM) is a useful tool for studying how drugs interact with skin and diagnosing skin disorders, despite some limitations.

COVID-19 may harm male fertility and damage the reproductive system.

Ablative fractional resurfacing could improve how well topical drugs penetrate the skin, but more research is needed to fine-tune the method.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

Nanotechnology could improve hair regrowth but faces challenges like complexity and safety concerns.

Fat tissue vesicles protect skin from UV damage better than stem cell vesicles.

Biopolymers are increasingly used in cosmetics for their non-toxicity and skin benefits, with future biotech advancements likely to expand their applications.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Gastric bypass surgery improved a woman's hormonal disorder without the need for medication.

The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

Phaeodactylum tricornutum extract helps hair follicle cells grow by activating the ERK1/2 pathway.

FPHL causes hair loss in women due to genetics and hormones; minoxidil and anti-androgens are treatments, and early intervention is advised.

Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.

Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

A mother's diet at conception can cause lasting genetic changes in her child.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Stem-cell therapy shows promise for skin conditions but needs more research.

Autologous Platelet and Extracellular Vesicle-Rich Plasma (PVRP) has potential in enhancing tissue regeneration and improving hair conditions, but its effectiveness varies due to individual differences.

Men are increasingly using energy-based skin treatments for workplace success, with lasers and other devices effectively improving skin and body appearance.

Adipose-derived stem cells show potential for skin rejuvenation and wound healing but require more research to overcome challenges and ensure safety.

New treatments and technologies in laser medicine show promise for improving skin conditions, fat reduction, cancer treatment, wound healing, and hair restoration.

PCOS and eating disorders are linked by hormonal imbalances, needing personalized treatment.