Maternal Nutrition at Conception Modulates DNA Methylation of Human Metastable Epialleles

April 2014 in “ Nature communications ”

Paula Domínguez-Salas, Sophie E. Moore, Maria S. Baker, Andrew W. Bergen, Sharon E. Cox, Roger Dyer, Anthony J. C. Fulford, Yongtao Guan, Eleonora Laritsky, Matt J. Silver, Gary E. Swan, Steven H. Zeisel, Sheila M. Innis, Robert A. Waterland, Andrew M. Prentice, Branwen J. Hennig

DNA methylation metastable epialleles methyl-donor nutrients plasma biomarkers lymphocytes hair follicles epigenetic changes

Studysummary This study found that the maternal nutritional status during early pregnancy significantly influenced epigenetic changes in offspring, as maternal diet altered DNA methylation at human metastable epialleles.

Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer ·

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