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5-alpha reductase inhibitors may cause sexual side effects, breast complications, and other health risks in men with hair loss.

Testosterone's muscle-building effects do not require its conversion to DHT.

Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.

Oral finasteride works better than topical minoxidil for hair growth, both are safe.

Finasteride and dutasteride effectively treat hair loss, but may cause side effects like sexual dysfunction and depression.

Both drugs lower DHT levels, with GI198745 being more effective.

5α-reductase inhibitors and alpha-1 adrenergic antagonists together effectively treat benign prostatic hyperplasia, with long-term benefits.

Long-term finasteride use doesn't change bone density or metabolism.

High doses of finasteride cause cell growth and tumors in mice.

The document concludes that sexual and psychiatric side effects from 5-alpha-reductase inhibitors are reported, but more high-quality research is needed to understand how often they occur.

Rats had lasting erectile problems after stopping a certain medication.

GI198745 is more potent and longer-lasting than finasteride, potentially better for treating hair loss.

Compounds from the plant Mammea siamensis may help treat hair loss.

α-Blockers and 5-ARIs for BPH can cause sexual dysfunction, including erectile and ejaculatory issues.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Hair loss drugs may cause sexual issues and infertility in men.

5α-reductase inhibitors may worsen sexual drive and spontaneous erections but don't worsen existing erectile or ejaculatory problems.

A specific gene mutation is linked to a hereditary form of dystonia that responds well to certain medications.

Finasteride causes abnormal growth in male mice cells at high doses.

The document concludes that women should not use 5-alpha-reductase inhibitors due to the risk of birth defects and limited effectiveness.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Finasteride effectively inhibits 5α reductase, while plant extracts like Permixon and Bazoton don't show significant results.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Certain drugs that block specific enzymes can help treat prostate diseases.

Thujae occidentalis semen extract may help treat male pattern baldness by blocking a hair loss-related enzyme and reducing hair loss in mice.

Black pepper leaf extract contains compounds that can block testosterone effects and promote hair growth.

Finasteride affects urinary steroid profiles and can potentially hide steroid abuse in sports drug testing.

Certain 4-azasteroids are effective at blocking the enzyme that processes testosterone in human skin and could help treat acne, excessive hair growth, and male pattern baldness.