Women With Clinically Significant Hirsutism Always Have Detectable Endocrinological Abnormalities

    December 1997 in “ Journal of The European Academy of Dermatology and Venereology ”
    Mohammad M. Alkhawajah
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    TLDR Most women with excessive hair growth have a hormonal cause.
    In a 1997 study of 120 Saudi women with clinically significant hirsutism, 78 were found to have hormonal abnormalities, with 85.9% showing elevated androgen levels. Polycystic ovary syndrome (PCOS) was the most common cause, present in 59% of patients, followed by hyperprolactinemia in 34.6%, and congenital adrenal hyperplasia in 14.1%. The study concluded that a two-step laboratory work-up could usually identify the cause of hirsutism and recommended detailed hormonal profiling for affected women. The findings suggest that idiopathic hirsutism is likely overused as a diagnosis and that most cases of hirsutism have an identifiable endocrinological cause.
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