Safety and Efficacy of Tofacitinib in 97 Alopecia Areata Patients

    Maryam Nasimi, Robabeh Abedini, Narges Ghandi, Amir Teymourpour, Hanie Babaie
    TLDR Tofacitinib is an effective and safe treatment for alopecia areata.
    This retrospective study evaluated the safety and efficacy of tofacitinib in 97 patients with alopecia areata (AA), alopecia totalis (AT), and alopecia universalis (AU) over at least 6 months. Results showed that 69.1% of patients experienced over 50% improvement in their Severity of Alopecia Tool (SALT) score, with 44.3% achieving a 90% or greater reduction. Patients with patchy AA responded better than those with AT and AU. Tofacitinib was well-tolerated, with no significant adverse events reported. The study concludes that tofacitinib is an effective treatment option for AA, AT, and AU.
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