April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” Targeting cholesterol, fatty acids, fibrosis, and mast cells may help treat CCCA.
May 2022 in “Dermatology practical & conceptual” Trichoscopy is crucial for diagnosing and managing androgenetic alopecia, showing increased vellus hairs, empty follicles, and fibrosis with severity.
September 2021 in “Eureka: Health Sciences” Androgenetic alopecia in women may be improved by targeting oxidative stress, inflammation, and fibrosis.
August 2014 in “Journal of clinical & experimental dermatology research” Platelet-released growth factors can treat hair loss by activating hair follicle stem cells, blocking certain pathways, and controlling inflammation and fibrosis.
April 2019 in “Journal of Investigative Dermatology” DPP4-positive fibroblasts play a major role in producing proteins that lead to skin fibrosis.
July 2021 in “Plastic and reconstructive surgery. Global open” Radiation therapy in breast cancer patients changes gene expression related to DNA damage, fibroblast growth, and hair follicle development, which could help improve treatment for radiation-induced fibrosis.
April 2019 in “Journal of Investigative Dermatology” New vitamin D3 forms need the vitamin D receptor to reduce fibrosis in human cells.
June 2018 in “The Journal of Sexual Medicine” Gray-scale ultrasound effectively detects erectile tissue fibrosis in young men with erectile dysfunction after using finasteride.
February 2017 in “The Journal of Sexual Medicine” Finasteride for hair loss can cause erectile dysfunction due to tissue fibrosis.
December 2016 in “The Journal of Sexual Medicine” Finasteride for hair loss may cause erectile dysfunction due to tissue fibrosis, and various factors contribute to female sexual dysfunction.
May 2022 in “Gastroenterology” Targeting NETs may help reduce fibrosis in Crohn's disease.
June 2008 in “British Journal of Dermatology” UK medical students lack dermatology education, liver biopsy patients with risk factors show more fibrosis, and certain fungi resist drugs due to melanin; genetics may influence female hair loss.
June 2014 in “British Journal of Dermatology” Eczema patients have a lower skin lipid to protein ratio, older and longer-staying hospital patients are more likely to get pressure ulcers, hair loss in AGA is linked to muscle degeneration, vitamin D deficiency is common in alopecia areata and linked to its severity, standard liver tests don't effectively detect fibrosis in psoriasis patients on methotrexate, and bullous pemphigoid patients have a higher death risk but combination therapy may reduce it.
June 2008 in “British Journal of Dermatology” Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.
488 citations,
July 2021 in “Cell” Fibroblasts are crucial for tissue repair and inflammation, and understanding them can help treat fibrotic diseases.
299 citations,
January 2018 in “Journal of Clinical Investigation” Different types of fibroblasts play various roles in diseases and healing, and more research on them could improve treatments.
220 citations,
March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
215 citations,
March 2011 in “Clinical Cancer Research” Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.
136 citations,
September 2019 in “Journal of Clinical Investigation” Dermal adipose tissue in mice can change and revert to help with skin health.
102 citations,
January 2003 in “Dermatology” Smoking may contribute to hair loss in men.
66 citations,
July 2015 in “Organogenesis” Wnt signaling is crucial for skin wound healing and reducing scars.
56 citations,
January 2015 in “Circulation” Finasteride helps reduce heart issues and improves heart function.
53 citations,
June 2020 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Animal models help study psoriasis but have limitations and don't fully mimic the human disease.
51 citations,
January 2006 in “Wound Repair and Regeneration” MRL/MpJ mice's skin wounds heal with scars, unlike their ear wounds which can regenerate.
49 citations,
August 2007 in “Dermatologic surgery” New treatments for acne scars are safer and more effective because we understand the causes better.
49 citations,
January 2003 in “Clinical and Experimental Dermatology” The document concludes that post-menopausal frontal fibrosing alopecia is a poorly understood condition that does not respond well to common treatments.
48 citations,
June 2020 in “Current Rheumatology Reports” Different types of fibroblasts play various roles in both healthy and diseased tissues, and understanding them better could improve treatments for fibrotic diseases.
42 citations,
June 2009 in “Journal of Cosmetic Dermatology” Hair loss in males involves inflammation, collagen buildup, and follicle damage, with severity increasing with age and baldness duration.
41 citations,
September 2017 in “Advanced Healthcare Materials” A special hydrogel helps heal skin without scars and regrows hair.
41 citations,
August 2015 in “The FASEB Journal” Blocking the Wnt/β‐catenin pathway can speed up wound healing, reduce scarring, and improve cartilage repair.