Grey-Scale Penile Ultrasound Findings in Young Men With Erectile Dysfunction Who Used Finasteride for Androgenic Alopecia

December 2016 in “ The Journal of Sexual Medicine ”

Irwin Goldstein, S. B. King, Steven L. Goldstein

finasteride androgenic alopecia erectile dysfunction corporal erectile tissue fibrosis dihydrotestosterone corporal smooth muscle cells apoptosis corporal connective tissue Propecia ED DHT

TLDR Finasteride for hair loss may cause erectile dysfunction due to tissue fibrosis, and various factors contribute to female sexual dysfunction.

This document contains two separate studies. The first study looked at eight men who developed erectile dysfunction (ED) after using finasteride for androgenic alopecia. The study found that all eight men had corporal erectile tissue fibrosis, which the researchers hypothesize is caused by low dihydrotestosterone (DHT) inducing corporal smooth muscle cells to undergo apoptosis and be replaced by corporal connective tissue. The second study was an online survey of women in the USA, which aimed to provide knowledge about sexual issues in the general population. The report found that there are several bio-psycho-social risk factors for female sexual dysfunction.

View this study on academic.oup.com →

Discuss this study in the Community →

Related Community Posts Join

6 / 1000+ results

community Evidenced Based Meta-Analyses and Systemic Reviews of Androgenic Alopecia and Treatments

in Research/Science 15 upvotes 4 years ago

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

community 1.5 years fin results ( 0.25mg ED)

in Progress Pictures 165 upvotes 2 months ago

A user shared their 1.5-year experience using 0.25mg finasteride daily for hair loss, noting significant hair quality improvements and reduced scalp itch but mild erectile dysfunction. They managed side effects with daily 2.5mg Cialis and 5mg citrulline and plan to continue this routine.

community Study of thousands of Fin users over 20 years finds no evidence of Fin induced sexual dysfunction

in Research/Science 376 upvotes 9 months ago

The conversation is about a finding that finasteride does not significantly increase the risk of sexual dysfunction, with users sharing mixed personal experiences regarding side effects.

community Why is human evolution like this 😂

in Chat 2 years ago

Why androgenic alopecia affects the scalp rather than other body parts, potential explanations for this phenomenon, treatments available to combat hair loss, and the implications of male attractiveness in modern society.

community Finasteride/dutasteride/etcetera. Clinical opinions of 1 GP and 1 leading urologist + links to reliable studies.

in Finasteride 9 upvotes 5 years ago

Finasteride is effective for treating male pattern baldness (MPB) with minimal side effects, and topical finasteride is similarly effective. Dutasteride is also effective but less understood, and Minoxidil is less effective than Finasteride.

community Treatment of Finasteride Induced Gynecomastia (Male breast tissue growth)

in Finasteride/Dutasteride 15 upvotes 4 years ago

Finasteride can cause gynecomastia, which may be reversible by stopping the drug and using selective estrogen receptor modulators (SERMs) like tamoxifen. Lifestyle changes such as weight loss and avoiding alcohol can also help, but surgery may be needed if the condition persists.

Related Research

3 / 3 results

research The Effects of Oral 5-Alpha Reductase Inhibitors on Penile Intracavernosal Pressures and Penile Morphology in a Rat Model

2 citations, May 2019 in “PubMed”

Oral finasteride and dutasteride may negatively affect erectile function in rats.

Finasteride, Not Tamsulosin, Increases Severity of Erectile Dysfunction and Decreases Testosterone Levels in Men With Benign Prostatic Hyperplasia

research Finasteride, Not Tamsulosin, Increases Severity of Erectile Dysfunction and Decreases Testosterone Levels in Men With Benign Prostatic Hyperplasia

20 citations, June 2015 in “Hormone Molecular Biology and Clinical Investigation”

Finasteride worsens erectile dysfunction and lowers testosterone in men with enlarged prostates, unlike tamsulosin.

Evaluation of Sexual Function With an International Index of Erectile Function in Subjects Taking Finasteride for Androgenetic Alopecia

research Evaluation of Sexual Function With an International Index of Erectile Function in Subjects Taking Finasteride for Androgenetic Alopecia

44 citations, July 2004 in “Archives of Dermatology”

Finasteride for hair loss has minimal impact on sexual function.