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Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

The skin has a complex immune system that is essential for protection and healing, requiring more research for better wound treatment.

Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Stem cells are crucial for skin repair and new treatments for chronic wounds.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Latanoprost can make eyelashes longer, thicker, and darker.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Bioprinting could improve wound healing but needs more development to match real skin.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

Fat-derived stem cells show promise for skin repair and reducing aging signs but need more research for consistent results.

TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

Stem cell plasticity is crucial for wound healing but can also contribute to cancer development.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Modern lifestyles, including poor diet, stress, and long-term use of certain medications, hinder the body's ability to heal from inflammation, leading to chronic diseases.

Macrophages help regrow hair by activating stem cells using AKT/β-catenin and TNF.

Hair color production is closely linked to the active growth phase of hair in mice and may also influence hair growth itself.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.

New single-cell analysis techniques are improving our understanding of stem cells and could help in treating diseases.

We need more research to better understand human hair follicle stem cells for improved treatments for hair loss and skin cancer.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

BMP2 and BMP7 have opposite roles in feather formation.

The skin protects the body and is constantly renewed by stem cells; disruptions can lead to cancer.

Circadian rhythms are crucial for stem cell function and tissue repair, and understanding them may improve aging and regeneration treatments.

Hair follicle regeneration needs special conditions and young cells.