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Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

JAGGED1 could help regenerate tissues for bone loss and heart damage if delivered correctly.

Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.

The HoxC gene cluster and its enhancers are essential for developing hair and nails in mammals.

A 19-year-old male with delayed puberty was successfully treated for a condition that prevents normal hormone production.

Shi-Bi-Man helps hair regrowth by activating the FGF pathway in cells.

Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.

Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.

Increased FGFR2b signaling, influenced by androgens, plays a role in causing acne.

Aging slows wound healing due to weaker cells and immune response.

Overactivating Hedgehog signaling makes hair follicle cells in mice grow hair faster and create more follicles.

Zebrafish need MYC and FGF to regenerate inner ear hair cells.

Researchers found genes and microRNAs that control curly fleece in Chinese Tan sheep.

Adding a second method to PROTACs could improve cancer treatment.

Cholesterol-modified siRNAs targeting certain genes increased hair growth in mice.

GDNF helps grow hair and heal skin wounds by acting on hair stem cells.

The new anti-acne treatment HA-P5 effectively reduces acne by targeting two key receptors and avoids an enzyme that can hinder treatment.

Retinoic acid affects male and female muscle energy use and function differently.

Eyelid cells share signaling components but differ in pathway activity.

The testes produce sperm and hormones essential for male development.

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

FGF12 is important for hair growth and could be targeted for hair loss treatment.

FGF5 spliceosomes inhibit rabbit hair growth by affecting gene expression.

Scientists are using clumps of special stem cells to improve organ repair.

FGF-1 causes spiral ganglion neurites to branch more.

FGFs-4, -8, and -9 have overlapping roles and are repeatedly used in tooth development.

Mice that can regenerate tissue have cells that pause in the cell cycle, which is important for healing, similar to axolotls.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

Mammals might fail to regenerate not because they lack the right cells, but because of how cells respond to their surroundings, and changing this environment could enhance regeneration.

Notch-related genes play a key role in the development and cycling of hair follicles.