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research Chronic telogen effluvium: Potential complication for clinical trials in female androgenetic alopecia?
CTE can distort results in hair growth trials, so exclude it carefully.
research Navigating Diagnostic Uncertainty: Frontal Fibrosing Alopecia Versus Keratosis Pilaris Atrophicans Faciei With Genetic Testing Insights
In this case study, a 36-year-old male with symptoms of keratosis pilaris atrophicans faciei and frontal fibrosing alopecia tested negative for a specific mutation, highlighting genetic testing's potential to improve diagnosis and treatment outcomes in these similar conditions.
research Effects of Crataegi Fructus Hot-Water Extract on Hair Growth and Growth Factor Gene Expression of Human Dermal Papilla Cells
Crataegi Fructus water extract may help treat hair loss.
research Follicular unit extraction megasession treatment of high‐grade androgenetic alopecia in Asians: Introducing novel principles for surgical design
This study found that FUE megasession with a specific surgical design is an effective and satisfactory treatment for Asian patients with high-grade male androgenetic alopecia, achieving natural hair density and high patient and doctor satisfaction, with minimal side effects.
research The role of ghrelin and ghrelin receptors in polycystic ovary syndrome
This study found that ghrelin and its receptor mRNA expression levels in follicular fluid cells are not significantly different between PCOS and non-PCOS patients, suggesting ghrelin may not play a role in PCOS pathogenesis.
research [The effect of cgVEGF164 on the growth of murine hair follicles].
This study found that transgenic mice expressing cgVEGF164 had increased hair follicle diameter and density, potentially linked to higher phosphorylation levels of ERK1/2, AKT1, and LEF1 proteins.
research 1405 Cellular and molecular characterization of sebaceous gland self-renewal and regeneration following complete genetic ablation
This study found that sebaceous glands can regenerate after PPARg deletion in adult skin, relying on the hair cycle and FGFR signaling.
research The Composite Galeal Frontalis Pericranial Flap Designed for Anterior Skull Base Surgery
This study reports that the composite galeal frontalis pericranial flap can be successfully used for reconstruction in anterior cranial base surgery, effectively sealing cerebrospinal fluid leaks, while minimizing complications like numbness and skin necrosis.
research Stem Cells in the Hair Follicle and Interfollicular Epidermis of Mice following Topical Application of Fluocinolone Acetonide
This study found that bulge keratinocytes in mice develop resistance to glucocorticoid treatment more slowly than interfollicular keratinocytes and do not significantly aid in repairing glucocorticoid-induced skin atrophy within five days.
research Commentary on Elimination of Sweat Glands Using the Follicular Unit Excision Technique
The technique removes sweat glands effectively.
research Impaired Lef1 activation accelerates iPSC-derived keratinocytes differentiation in Hutchinson-Gilford Progeria Syndrome
In this study, researchers found that correcting the HGPS mutation with Adenine base editing partially rescued accelerated skin cell differentiation and reduced cell death in patient-derived stem cells.
research Selective blockade of γc pathway ameliorates alopecia areata in a humanized murine model
This study reported that the anti-γc antibody hC2 restored hair follicle homeostasis and suppressed hair loss in an AA-like mouse model by inhibiting autoreactive T-cell activity, suggesting that hC2 may offer a safer and more effective treatment for alopecia areata compared to current Jak inhibitors.
research Modulation of glucocorticoid action and the treatment of type-2 diabetes
This review discusses the potential of targeting glucocorticoid action as a treatment strategy for obesity and type-2 diabetes, highlighting promising animal study results but reports no new clinical findings.
research Evaluation of Efficacy of Water-Soluble Fraction of Rhus semialata Gall Extract and Penta-O-Galloyl-β-D-Glucose on Mitigation of Hair Loss: An In Vitro and Randomized Double-Blind Placebo-Controlled Clinical Study
In this study, the researchers found that the water-soluble fraction of Rhus semialata gall extract and its component Penta-O-Galloyl-β-D-Glucose promoted hair growth in human dermal papilla cells, and clinical trials supported these findings, showing improved hair density and appearance compared to placebo.
research Bio-multifunctional alginate/chitosan/fucoidan sponges with enhanced angiogenesis and hair follicle regeneration for promoting full-thickness wound healing
In this study, ACF sponges with 10% fucoidan significantly promoted wound healing and hair follicle regeneration in rats, showing improved hemostatic and antibacterial performance compared to other formulations.
research Green Formulation and Evaluation of a Sustainable Herbal Hair Gel Using Curry Leaf, Flaxseed, And Aloe Vera Extracts: An Eco-Friendly Cosmetic Approach
This study formulated and tested eco-friendly herbal hair gels using extracts from curry leaf, flaxseed, and Aloe vera, finding that formulation F9 showed optimal viscosity, spreadability, superior antifungal activity, and stability over six months, making it a promising sustainable alternative to synthetic hair gels.
research Microsporum gypseum isolated from a feline case of dermatophytosis
This study confirmed that a rare dermatophyte infection in a young cat was caused by Arthroderma gypseum, identified using molecular analyses.
research Exploring the Drug-Loading and Release Ability of FucoPol Hydrogel Membranes
This study found that FucoPol hydrogel membranes can effectively deliver model drugs such as caffeine and diclofenac sodium via different loading methods, with notable mechanical and release properties, suggesting their potential as platforms for topical drug delivery.
research DEVELOPMENT OF GARCINIA CAMBOGIA ENRICHED NUTRI BITE FOR THE MANAGEMENT OF PCOS
This article discusses the development of a Garcinia Cambogia enriched snack intended for managing PCOS but reports no new clinical results.
research 증례 : Gefitinib에 의해 유발된 반흔성 탈모증
This article presents a rare case of cicatricial alopecia in a 59-year-old woman after using the epidermal growth factor receptor inhibitor gefitinib.
research Melanocytes from the outer root sheath of human hair and epidermal melanocytes display improved melanotic features in the niche provided by cGEL, oligomer-cross-linked gelatin-based hydrogel
This study found that a novel hydrogel scaffold, cGEL, significantly increased melanin production and melanotic gene expression in human melanocytes compared to other graft materials, suggesting its potential as a superior carrier for skin grafting.
research Epidermal Growth Factor Promotes Proliferation and Migration of Follicular Outer Root Sheath Cells via Wnt/β-Catenin Signaling
This study reports that EGF at specific concentrations promotes the proliferation and migration of hair follicle ORS cells by activating the Wnt/β-catenin signaling pathway in vitro.
research Gonadal Suppressive and Cross‐Sex Hormone Therapy for Gender Dysphoria in Adolescents and Adults
This review covers cross-sex hormone therapy for gender dysphoria, noting improvements in psychological symptoms and quality of life but lacking definitive long-term safety data.
research A homozygous single T deletion found in the GGCX gene with PXE-like phenotypes
This study reports a case of GGCX syndrome in a 55-year-old Japanese male, characterized by PXE-like symptoms and coagulation deficiency, with an unreported phenotype of possible spinocerebellar degeneration.
research A case of cutis verticis gyrata developing in a patient with primary scarring alopecia: A unique presentation of a rare disorder
This case report describes a 39-year-old female with cutis verticis gyrata and cicatricial alopecia, emphasizing the need for further understanding of the potential genetic associations and underlying mechanisms.
research 41761 Alpha-gal Syndrome for the Dermatologist
Dermatologists should consider alpha-gal syndrome in patients with unexplained chronic skin issues.
research Integrated Analysis of Methylome and Transcriptome Changes Reveals the Underlying Regulatory Signatures Driving Curly Wool Transformation in Chinese Zhongwei Goats
This study found that stage-specific epigenetic changes, particularly involving the gene PDGFC, may affect wool fiber development in Zhongwei goats, potentially serving as a biomarker for fur goat selection.
research HAIR DEPIGMENTATION AND DERMATITIS – AN UNEXPECTED PRESENTATION OF CYSTIC FIBROSIS
This case study describes a 3.5-month-old girl with cystic fibrosis who experienced hair and skin depigmentation, which resolved after treatment with pancreatic enzymes and vitamins.
research Hair follicle targeting via gelatin coated transferosomes loaded with tofacitinib citrate for enhanced treatment of alopecia areata: Clinical evaluation of alopecia areata patients
In this study, gelatin-coated transferosomes were developed to deliver tofacitinib specifically to hair follicles, resulting in 80% hair regrowth in alopecia areata patients with recalcitrant lesions after 12 weeks of treatment.