1 citations
,
July 2025 in “Journal of Chemical Biological and Physical Sciences” This study found that women with polycystic ovary syndrome have higher rates of infertility, shorter reproductive spans, and poorer fertility outcomes compared to healthy controls.
16 citations
,
June 2022 in “Transgender Health” This review suggests that oocyte retrieval may be viable for transgender men on testosterone therapy, with potentially manageable effects on fertility preservation without requiring extensive hormone suspension.
12 citations
,
February 2025 in “Women s Health” This paper reports that while metformin may improve fertility outcomes and reduce miscarriage rates in women with PCOS, its efficacy can differ depending on the specific treatment combination used.
45 citations
,
March 2015 in “Clinical Endocrinology” This article reviews the use of cross-sex hormonal therapy in transmen and reports that it is reasonably safe, suggesting monitoring should be frequent initially but can be less frequent over time.
222 citations
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January 2014 in “International journal of reproductive medicine” This paper reviews the complex pathophysiology of polycystic ovary syndrome, exploring how hormonal and metabolic disturbances contribute to its symptoms and related health risks, but it presents no new findings.
69 citations
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September 2006 in “Human Reproduction” This study found that CD45RO+ cells, a subtype of T lymphocytes, were notably reduced in the ovarian follicles of women with PCOS, which may contribute to the condition's pathogenesis.
14 citations
,
January 2013 in “Indian Journal of Endocrinology and Metabolism” This review discusses the fertility and pregnancy challenges faced by women with congenital adrenal hyperplasia due to 21-hydroxylase deficiency and reports no new research findings.
December 2025 in “Lviv clinical bulletin” This review found that platelet-rich plasma therapy may enhance ovarian repair and fertility outcomes in ovarian insufficiency, but notes that optimal usage and long-term effects require further investigation.
2 citations
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December 2016 in “Clinical and Experimental Obstetrics & Gynecology” This study found that women with PCOS and factors like primary infertility, familial history of type 2 diabetes, and specific lipid profiles tend to have less favorable fertility treatment outcomes.
January 2026 in “Annals of Clinical Endocrinology and Metabolism” This narrative review summarizes evidence on NAD⁺ biosynthesis and turnover, highlighting that while NAD⁺ precursors like NR and NMN consistently boost NAD⁺ levels in preclinical and human studies, clinical outcome results remain varied, indicating a need for more standardized human trials.
October 2025 in “International Journal of Reproduction Contraception Obstetrics and Gynecology” This study found that Myoinositol and D-chiro inositol treatment improved fertility outcomes in women with PCOS, particularly in Phenotypes A and D, but larger studies are needed to confirm these results.
5 citations
,
October 2021 in “Journal of Ovarian Research” This review indicates promising potential for cinnamon supplementation to improve metabolic outcomes in PCOS, but more clinical trials with higher doses and longer durations are needed to confirm these effects.
3 citations
,
July 2025 in “Obesity Facts” This review examines how GLP-1 receptor agonists might impact metabolic and reproductive outcomes in polycystic ovary syndrome, but it reports no new clinical findings and highlights the need for further research.
1 citations
,
July 2024 in “Quality in Sport” This review discusses the impact of lifestyle interventions on managing polycystic ovary syndrome and concludes that such modifications can significantly improve clinical outcomes and the health profile of patients, but reports no new results.
October 2024 in “Andrology” This study investigated paternal drug exposure using FDA data and identified significant associations with reproductive health risks, including congenital anomalies linked to immunosuppressive drugs, and emphasized specific risk combinations like biologics and abortion, diazepam and small for date baby, and finasteride and cryptorchidism.
June 2026 in “Frontiers in Nutrition” This study provides a narrative review suggesting GLP-1 receptor agonists could optimize metabolic health before conception in women with PCOS, but not necessarily improve fertility outcomes, emphasizing individualized use and the need for further research to confirm their reproductive benefits and safety.
3 citations
,
April 2020 in “Journal of Mind and Medical Sciences” This review discusses the reproductive challenges and potential pathophysiological mechanisms related to anorexia nervosa, noting possible long-term effects on fertility and pregnancy outcomes.
166 citations
,
October 2018 in “Endocrine Reviews” This review discusses the effects of hormonal treatments on the physical and mental health of transgender individuals, reporting significant reductions in mental health issues following treatment, but calls for more research on long-term and nonbinary outcomes.
January 2015 in “International journal of reproduction, contraception, obstetrics and gynecology” This study found a 6.39% prevalence of PCOS among women at a medical institute in India, with high rates of infertility and menstrual irregularities suggesting the need for early diagnosis and management.
March 2014 in “Fertility and Sterility” The April 2014 issue of "Fertility and Sterility" discussed various reproductive health topics, including hormone therapy benefits, sperm and genetic factors in male infertility, and the link between PCOS and diabetes.
April 2025 in “Journal of Controversies in Obstetrics & Gynecology and Pediatrics” This study found that vitamin D supplementation significantly improved clinical pregnancy rates in women with polycystic ovary syndrome treated at a Turkish infertility clinic, though it did not affect live birth or miscarriage rates.
70 citations
,
April 2013 in “Endocrine” This review found that lifestyle changes, such as diet and exercise, are beneficial for managing metabolic and endocrine abnormalities in obese patients with PCOS and suggests combining these with anti-obesity agents for enhanced effects.
January 2018 in “Murdoch Research Repository (Murdoch University)” This study identified putative causal mutations for PCOS among first-degree relatives, although functional analysis of a specific GDF9 mutation was unsuccessful.
April 2026 in “Biomolecules” This review highlights recent advancements in molecular understanding and treatment approaches for PCOS, including innovative drug delivery systems and AI-driven precision medicine, but provides no new clinical results.
9 citations
,
March 2021 in “Hormones” This review discusses how COVID-19 may affect gonadal function and potential gender differences, but reports no clinical results; it highlights possible mechanisms and new treatment approaches from recent literature.
17 citations
,
February 2020 in “Journal of Pediatric and Adolescent Gynecology” This review discusses medical interventions that reproductive health experts can provide to transgender and gender diverse youth and reports no new clinical results.
6 citations
,
July 2024 in “Cureus” This review explores the applications of magnetized water in agriculture and medicine and notes potential benefits for human health, but it presents no new experimental findings.
117 citations
,
May 2017 in “Human Reproduction Update” This review examines the epidemiology, pathophysiology, diagnosis, and management strategies for non-classic congenital hyperplasia due to 21-hydroxylase deficiency, and provides evidence-based recommendations for its treatment and genetic counseling.
18 citations
,
December 2014 in “Obstetrics and Gynecology Clinics of North America” This study suggests that weight loss can improve fertility outcomes in overweight and obese women with PCOS, and letrozole should be considered the new first-line treatment over clomiphene citrate for anovulatory infertility in this population.
15 citations
,
November 2024 in “EClinicalMedicine” This abstract does not report specific study results but describes the funding and collaboration involved in developing the International PCOS Guidelines by multiple health research organizations.