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This study found that androgen signaling has complex effects on bone formation in male AR3.6-transgenic mice, with varying impacts based on the embryonic lineage of cells.

This narrative review highlights the critical role of intracrine hormone production in peripheral tissues, suggesting that continuous-release subcutaneous testosterone pellet therapy may offer a more effective symptom-driven approach for aging populations, though large-scale randomized controlled trials are needed for confirmation.

This study suggests that PKCß plays a critical role in modulating the dermal inflammatory microenvironment in response to dietary lipids in mice.

This study concluded that both phosphatidylcholine alone and with organic silicium effectively reduced submental fat, achieving optimal results after three sessions with mild and temporary adverse effects.

This study found that removing PPARγ specifically from mouse adipose tissue led to severe fat loss, insulin resistance, diabetes, and associated metabolic abnormalities.

This study found that a 400-mg dose of oral testosterone with dutasteride increases serum testosterone levels for 8–10 hours in hypogonadal men, with the nanomilled formulation unaffected by food, suggesting a practical twice-daily therapy option.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

This review discusses the safety of testosterone therapy for postmenopausal women and concludes that, aside from hirsutism and acne, it appears safe at physiological doses for several years, though more long-term studies are needed.

This review discusses the potential role of androgen receptor CAG repeat polymorphism testing in hypogonadism management for both sexes, but its clinical utility remains unclear and requires further investigation.

Testosterone therapy aims to treat hormone deficiencies and various conditions safely and effectively, but requires careful patient monitoring due to potential side effects.

This report presents the first known case of localized nonscarring and scarring alopecia following autologous fat grafting and reviews literature on alopecia caused by facial fillers, suggesting vascular compromise as a potential cause.

This study found that injecting minced fat into the facial artery of rabbits was associated with higher rates of ophthalmic complications and mortality compared to fat granules or fat lipids.

This study found that honokiol inhibits enzymes related to testosterone degradation in vitro, suggesting its potential as a lead compound for developing antiaging bioactive ingredients for men.

This study found that men with more advanced androgenetic alopecia had increased epicardial fat thickness, suggesting a potential link to coronary risk.

This study used enhanced Raman spectroscopy to successfully detect ultra-low levels of free testosterone in women with PCOS, suggesting a potential low-cost method for early diagnosis.

This research discusses the author's findings on methods for harvesting and preparing fat tissue for transplantation, highlighting rare but serious complications reported in animal studies and the use of conditioning devices.

This review examines the development of cardiovascular risk factors related to testosterone levels in PCOS women and reports no new clinical results.

This study found that Piper nigrum leaf extract showed in vivo anti-androgenic activity and potent 5α-reductase inhibitory effects, with piperine and (−)-cubebin identified as active components.

This review examines the roles of androgens in women's health and provides recommendations for androgen therapy but reports no new results.

This study found that both ethanol and aqueous extracts of Lepidium sativum seeds improved insulin signaling and reduced obesity-related metabolic changes in high-fat diet-fed rats, suggesting potential as a dietary supplement.

This review highlights the potential therapeutic applications of nandrolone, an anabolic steroid, for male health, but notes that more human studies are needed due to limited existing literature.

In this review and meta-analysis, the authors concluded that 5α-reductase inhibitor therapy is not consistently associated with significant increases in serum testosterone levels in men.

This study found that the BP-3 extract from Boesenbergia rotunda, rich in panduratin A, demonstrated strong anti-adipogenesis and lipolysis effects on preadipocyte cells at non-toxic concentrations, and when formulated into a serum reduced thigh circumference and improved skin firmness in a human trial.

This study found that concentrated nanofat, used alone or with decellularized nanofat, may enhance hair growth in mice by activating dermal papilla cells and the anagen phase.

This review discusses the potential of using human hair proteomics for non-invasive diagnostic and forensic applications but reports no new results; the authors highlight areas needing further research.

This study found that ethanol extract of Syzygium aromaticum (clove) leaves significantly improved lipid profiles and increased body weight in testosterone-induced benign prostatic hyperplasia rats, suggesting potential anti-hyperlipidemic effects and modulation of body weight through metabolic activity.

In this animal study, AGO (agomelatine) effectively alleviated testosterone-induced benign prostatic hyperplasia in rats by reducing oxidative stress and inflammation, indicating its potential as a therapeutic option for managing BPH through specific signaling pathways.

This review describes the clinical features of testosterone deficiency syndrome in aging men but reports no new experimental findings, highlighting the need for clinical recognition and treatment of TDS.

In a rat model of benign prostatic hyperplasia, this study found that purple corn extract may improve symptoms by inhibiting prostate enlargement, reducing androgen receptor signaling, and exerting anti-inflammatory effects.

This study found a weak positive correlation between dihydrotestosterone levels and C-reactive protein in COVID-19 patients, particularly in those with low testosterone, suggesting potential inflammatory effects.