June 2022 in “Journal of Dermatology Research” Using 448-kHz Capacitive-Resistive Electrothermal Therapy can help increase hair density and prevent hair loss in women.
374 citations
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July 2016 in “The Lancet. Diabetes & endocrinology” Cushing's syndrome can cause serious health problems, and early treatment is crucial, but some issues may remain after treatment.
341 citations
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November 2009 in “The FASEB Journal” Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.
321 citations
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March 2015 in “Nature” Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
245 citations
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January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
233 citations
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February 2018 in “Polymers” Chitin and chitosan are useful in cosmetics for oral care, haircare, and skincare, including UV protection and strength improvement.
220 citations
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March 2020 in “Advanced functional materials” Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.
147 citations
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September 2006 in “Developmental Cell” Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.
143 citations
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November 2008 in “Experimental gerontology” Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
137 citations
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September 2005 in “Proceedings of the National Academy of Sciences of the United States of America” The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
133 citations
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June 2016 in “Cell Host & Microbe” Human dermal fibroblasts are the main cells targeted by a virus that can cause a deadly skin cancer, and a certain inhibitor can effectively block this infection.
130 citations
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August 2020 in “Drug Design Development and Therapy” Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.
119 citations
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March 2020 in “Frontiers in Bioengineering and Biotechnology” Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.
118 citations
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May 2015 in “European journal of pharmaceutics and biopharmaceutics” The hydrogel with a 1:3 ratio of hydroxyethyl cellulose to hyaluronic acid is effective for delivering drugs through the skin to treat acne.
97 citations
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March 2002 in “Molecular and cellular biology” Mutant CDP/Cux protein causes hair defects and reduced male fertility in mice.
94 citations
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September 2014 in “Therapeutic Delivery” Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
91 citations
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January 2011 in “Tissue Engineering Part A” Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.
87 citations
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July 2016 in “Development” Blocking β-catenin in skin cells improves hair growth during wound healing.
65 citations
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August 2007 in “Experimental Dermatology” Human hair follicles can make and process prostaglandins, which may affect hair growth.
65 citations
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September 2004 in “The American journal of pathology” Blocking BMP signaling causes hair loss and disrupts hair growth cycles.
54 citations
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January 2016 in “Methods in enzymology on CD-ROM/Methods in enzymology” Keratins are important for skin cell health and their problems can cause diseases.
53 citations
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February 2011 in “Diabetes” People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
50 citations
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March 2007 in “Clinical obstetrics and gynecology” Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.
49 citations
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October 2009 in “Cancer research” Disrupting Stat3 in hair follicle stem cells greatly reduces skin tumor formation.
47 citations
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April 2021 in “Pharmacological research” Exosomes can improve skin health and offer new treatments for skin repair and rejuvenation.
47 citations
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May 2021 in “Polymers” Jojoba oil is highly valued for its diverse medicinal and industrial uses.
47 citations
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September 2014 in “European Journal of Pharmaceutics and Biopharmaceutics” Scientists created a gel with nanoparticles to deliver medicine to hair follicles effectively.
45 citations
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January 2010 in “Journal of Investigative Dermatology” The S100A4 protein is more common in psoriatic skin and could be a target for treating psoriasis.
43 citations
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July 2019 in “Stem Cells International” Advancements in creating skin grafts with biomaterials and stem cells are promising, but more research is needed for clinical application.
40 citations
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December 2015 in “Journal of Cellular Biochemistry” Cysteine helps maintain keratin production in skin cells even when iron is low.