A Case of 300 Pound Weight Loss, Malabsorption, Malnutrition, and Protein-Losing Enteropathy Due to Systemic Lupus Erythematosus of the Small Intestine
September 2007
in “
The American Journal of Gastroenterology
”
TLDR Recognizing lupus as a cause of severe gut issues is crucial for effective treatment.
This case study detailed a 55-year-old female with Systemic Lupus Erythematosis (SLE) who experienced severe malabsorption, malnutrition, and a 300-pound weight loss due to extensive small bowel inflammation. Despite initial treatments, her condition worsened, leading to ICU admission. Diagnostic tests revealed lupus-associated enteritis, confirmed by positive lupus serologies and small bowel pathology. Treatment with IV solumedrol and TPN improved her condition, allowing discharge on oral prednisone and azathioprine. This case highlighted the importance of recognizing SLE as a potential cause of severe gastrointestinal issues to ensure effective treatment and improve survival outcomes.
