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      research Macrocytosis and pseudoalbinism: Manifestations of selenium deficiency

      126 citations , November 1987 in “The Journal of Pediatrics”
      This study reports that selenium deficiency in children on long-term total parenteral nutrition may lead to symptoms like erythrocyte macrocytosis and skin and hair depigmentation, which improved with selenium supplementation.

      research Acquired Zinc Deficiency

      73 citations , May 1976 in “JAMA”
      This case report associates severe zinc deficiency with long-term total parenteral nutrition, suggesting the need for trace element supplementation in such nutritional management.

      research Zinc deficiency during total parenteral nutrition in childhood

      26 citations , February 1978 in “Journal of Pediatric Surgery”
      This study found that long-term total parenteral nutrition in pediatric patients led to severe zinc deficiency, which improved with intravenous zinc therapy, highlighting the need for adequate zinc inclusion in nutritional solutions.

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