This research review found that spironolactone can significantly improve acne severity more effectively than a placebo, with 73.3% of patients reporting satisfaction despite a 26.7% rate of adverse events among the 1,548 participants studied.
May 2024 in “Journal of Pakistan Association of Dermatologists” In this randomized control trial, researchers reported that topical calcipotriol was more effective than topical tacrolimus in promoting hair growth for patients with alopecia areata over a 6-month period, with a statistically significant difference in efficacy.
This study observed that combining PRP and Tressfix Serum significantly improved hair regrowth and reduced microRNA expression linked to Chronic Telogen Effluvium compared to using either treatment alone.
April 2024 in “Al-Azhar International Medical Journal /Al-Azhar International Medical Journal” This study at Al-Azhar University Hospitals found that combining a fractional CO2 laser or microneedling with topical 5-Fluorouracil (5-FU) is more effective and safe for treating vitiligo than using either treatment alone, offering a new therapeutic option for patients.
April 2024 in “Journal of Pakistan Association of Dermatologists” This study found that adding procapil to minoxidil was more effective than minoxidil alone in improving hair count, patient satisfaction, and dermatologist assessment scores for treating androgenetic alopecia over 12 months.
October 2023 in “Journal of Pakistan Association of Dermatologists” This randomized control trial reported that patients with alopecia areata typically have lower serum Vitamin D levels, and treatment with topical vitamin D3 analogue calcipotriol led to significant hair regrowth in 71% of participants over six months.
May 2023 in “Research Square (Research Square)” This study found that Muslim women who wear the hijab experienced an earlier onset of non-scarring alopecia compared to those who do not, with vitamin D deficiency and seborrheic dermatitis potentially contributing to the development of telogen effluvium in this group.
April 2023 in “Egyptian journal of Immunology” This study found that human platelet lysate supported mesenchymal stem cell growth as effectively as fetal bovine serum, while fetal bovine serum was more effective for hepatocyte proliferation.
December 2020 in “American Journal of Transplantation” This article discusses a journal-based CME activity on rare viral skin eruptions in pediatric transplant patients and reports no new clinical results; it aims to improve physicians' knowledge and treatment of this condition.
October 2011 in “Iranian Journal of Dermatology” This study found that men with androgenic alopecia had significantly higher levels of lipoprotein (a), a risk factor for coronary artery disease, compared to men with normal hair.
4 citations
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January 2020 in “Obstetrics and Gynecology Reports” This study found that obese Egyptian women with polycystic ovary syndrome had significantly lower serum 25-OH vitamin D levels compared to non-obese women with the condition.
2 citations
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June 2024 in “Medical Journal of Babylon” In this study, researchers observed significantly higher CD8+ T cell levels in Iraqi patients with Alopecia areata compared to healthy controls, alongside concluding that the condition is more prevalent in men.
1 citations
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August 2025 in “The Egyptian Journal of Internal Medicine” This paper reviews obesity diagnosis and screening methods, emphasizing BMI's practicality in low- and middle-income countries, but provides no new clinical results.
1 citations
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January 2023 in “The Egyptian Journal of Hospital Medicine” This study found that combining platelet-rich plasma with microneedling and subcision was effective in treating atrophic acne scars in over 80% of patients with minimal adverse effects.
1 citations
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January 2021 in “Brazilian Journal of Medical and Biological Research” In this study, maternal exposure to constant light significantly altered the neonatal skin structure in rabbits, associated with reduced maternal melatonin levels.
This study evaluated the effect of intralesional injections of lyophilized Platelet Derived Growth Factors in 42 patients with Peyronie's disease and found significant reductions in penile curvature and plaque size, along with improvements in Peyronie's Disease Questionnaire scores, suggesting a potential treatment role.
This critical review highlights the anti-carcinogenic properties of luteolin, a plant flavonoid, and examines how encapsulating luteolin in nanoformulations may overcome its bioavailability challenges, potentially enhancing its effectiveness as a safer cancer treatment according to this source.
June 2024 in “Journal of Ayub Medical College Abbottabad” This study concluded that adding 5% topical Procapil to PRP therapy provided better outcomes for androgenetic alopecia than PRP alone, as assessed by dermatologist evaluations and patient satisfaction.
January 2024 in “Universiti Putra Malaysia Institutional Repository (Universiti Putra Malaysia)” In this review, the authors discuss the anti-cancer potential of luteolin, a plant-derived compound, highlighting its limitations in bioavailability and solubility, as well as exploring the enhanced efficacy of luteolin when formulated in nanoparticles for cancer treatment.
August 2023 in “American Journal of Hospice and Palliative Medicine” This study describes common skin disorders in palliative care patients, emphasizing that conditions like xerosis, pressure ulcers, and fungal infections often require symptomatic treatment focused on quality of life rather than cure, due to limited life expectancy and potential treatment burdens.
October 2022 in “Journal of pharmaceutical negative results” This study found that patients with Alopecia areata in Iraq had significantly higher levels of CD4+, CD39+, and FOXP3+ Treg cells in their blood compared to healthy controls.
February 2013 in “Jurnal Biomedik : JBM” This article discusses therapeutic options for managing androgenic alopecia but reports no new clinical results, recommending selective and safe drugs such as growth stimulators and DHT inhibitors.
184 citations
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October 2007 in “Proceedings of the National Academy of Sciences of the United States of America” This study found that sulforaphane-rich broccoli sprout extracts reduced UV-induced erythema by 37.7% in humans, suggesting a protective strategy against UVR damage.
68 citations
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March 2002 in “Journal of pharmaceutical sciences” This study found that nonionic liposomes were the most effective vehicle for delivering reporter genes into the skin of rat pups, compared to other liposome and nonliposome formulations.
36 citations
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May 2020 in “Journal of the European Academy of Dermatology and Venereology” Dermatologists should watch for skin symptoms in COVID-19 patients, prioritize urgent cases, and use telemedicine.
30 citations
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December 2019 in “PLoS ONE” This study found that formulating raloxifene in nano-lipid carriers significantly enhanced its permeation and cytotoxicity against cancer cells compared to raw raloxifene.
23 citations
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January 2010 in “Journal of Medical Primatology” This study found that alopecia in captive Rhesus macaques may be linked to chronic hypersensitivity dermatitis with CD4+ cell inflammation, possibly influenced by altered housing and reduced pathogen exposure.
19 citations
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May 2006 in “Clinical and Experimental Dermatology” This study identified a novel insertion mutation in the hairless gene that may contribute to the development of congenital atrichia with papular lesions in a Pakistani family.
11 citations
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August 2020 in “Diabetes” This study found that testosterone enhances insulin secretion in human pancreatic islets by being converted into DHT and E2, processes that are necessary for this effect.
5 citations
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February 2016 in “International Journal of Cancer” In this mouse study, applying a vasoconstrictor before chemotherapy did not create a leukemia sanctuary or significantly impact survival outcomes, suggesting it may not interfere with leukemia treatment.