Role of Sebaceous Glands in Androgenic Alopecia

    February 2013 in “ Jurnal Biomedik : JBM ”
    Rahma M Fahruddin, Sonny J. R. Kalangi, Taufiq F Pasiak
    Image of study
    TLDR The sebaceous gland plays a significant role in hair loss and thinning, and using growth stimulators, DHT inhibitors, anti-inflammatory drugs, anti-androgens, and super oxide dismuse substances can help manage it.
    The document "PERAN KELENJAR SEBASEA PADA ALOPESIA ANDROGENIK" from 2013 discussed the role of the sebaceous gland in androgenic alopecia, the most common cause of hair loss and thinning in both men and women. The authors explained that each of the approximately 100,000 hair shafts on the scalp has a three-phase growth cycle (anagen, catagen, and telogen), leading to a mosaic growth pattern where hair does not grow and fall out simultaneously. The sebaceous gland was identified as playing a significant role in the occurrence of androgenic alopecia. The authors also highlighted the need for selective and high safety drugs in managing androgenic alopecia, suggesting the use of growth stimulators, DHT inhibitors, anti-inflammatory drugs, anti-androgens, and super oxide dismuse substances.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 75 results

      community "DHT Itch" and onset Seborrheic Dermatitis

      in Research/Science  76 upvotes 1 year ago
      The post and conversation discuss the link between DHT (a hormone), scalp itchiness, and hair loss. Some users share their experiences and treatments, including the use of fluconazole, corticosteroids, and ketoconazole shampoo, with one user suspecting minoxidil as a potential cause of their symptoms.
      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      in Research  830 upvotes 9 months ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community DHT Harms Scalp Microbiome: DHT Itch is REAL

      in Research/Science  407 upvotes 1 month ago
      Increased Malassezia and Cutibacterium in the scalp microbiome are linked to higher sebum production and inflammation in androgenetic alopecia (AGA). Treatments include ciclopirox shampoo, benzoyl peroxide shampoo, clobetasol propionate, calcipotriol, minoxidil, finasteride, and dutasteride.

      community A hill on which I will die: The DHT itch absolutely exists

      in Research/Science  210 upvotes 1 year ago
      The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

    Related Research

    6 / 6 results