July 2025 in “Current Issues in Molecular Biology” This study evaluated the safety and efficacy of Bio-Pulsed avian mesenchymal stem cell-derived small extracellular vesicles when applied topically, finding significant improvements in hair growth, skin rejuvenation, and regenerative microRNA presence among 60 human participants without adverse events.
June 2025 in “Journal of Cosmetic Dermatology” This study found that among various treatments for male androgenetic alopecia, dutasteride 0.5 mg/day was the most effective option overall. Additionally, among FDA-approved treatments, topical minoxidil 5% was the most effective topical therapy, and finasteride 1 mg/day was the most effective oral therapy.
June 2025 in “Naunyn-Schmiedeberg s Archives of Pharmacology” This literature review reports that certain herbal remedies, such as rosemary, green tea, and ginseng, have shown promise in promoting hair growth and improving hair density, though variability and study design limitations highlight the need for more rigorous research.
June 2025 in “International Journal of Dermatology” This review highlights that exosomes are showing promise as therapeutic, prognostic, and diagnostic agents in dermatology, with clinical studies suggesting efficacy for skin aging, scarring, hair restoration, and inflammatory conditions, though challenges in standardization and regulation remain.
February 2025 in “Healthcare” In this systematic review, the researchers observed that topical caffeine preparations appear safe and effective against hair loss, but most studies had low-quality evidence due to design flaws, indicating the need for better-designed trials before drawing definitive conclusions.
April 2024 in “Prostate international” In this study using Mendelian randomization analysis, researchers found no causal relationship between androgenic alopecia and prostate cancer risk, suggesting that previously observed associations in epidemiological studies might not be causal.
October 2023 in “Acta dermato-venereologica” Minoxidil and platelet-rich plasma can help turn thin hair into thicker hair in male pattern baldness.
October 2023 in “Toxicology and Applied Pharmacology” This study found that finasteride and minoxidil act as hormone disruptors in mice, with finasteride having a more significant association with reproductive injuries, such as damage to the epididymis and reduced semen volume.
April 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” The researchers reported that DHT may reduce the inflammatory responses induced by C. acnes in androgen-sensitive human sebocyte cells, suggesting a potential link between androgens and infection in sebaceous disorders.
March 2023 in “Current Pharmaceutical Design” This study found that spironolactone significantly reduced hirsutism scores in women with idiopathic hirsutism compared to finasteride and cyproterone acetate but showed no significant difference among women with PCOS compared to flutamide and finasteride, and it was well tolerated overall.
25 citations
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August 2022 in “Frontiers in Reproductive Health” This review discusses the use of platelet-rich plasma injections for treating erectile dysfunction, noting the potential for regenerative medicine to reverse or halt disease progression, but it reports no new clinical results.
15 citations
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April 2020 in “Journal of Dermatological Treatment” This study suggests platelet-rich plasma may be more effective than other non-surgical treatments for male androgenetic alopecia, while low-level laser therapy ranks highest for women; however, the evidence quality was low.
12 citations
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February 2014 in “PLoS ONE” This study observed high expression of mTOR pathway effectors in fibrous papules and TSC-associated angiofibromas, suggesting that topical rapamycin might be an effective treatment for fibrous papules.
8 citations
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May 2025 in “Acta Obstetricia Et Gynecologica Scandinavica” This meta-analysis reported that dienogest and combined oral contraceptives had comparable efficacy and tolerability for endometriosis treatment, with therapeutic choice suggested to be based on patient preference and clinical history.
7 citations
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March 2025 in “Aesthetic Plastic Surgery” 5 citations
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January 2020 in “Skin Appendage Disorders” In this study, a water-soluble nail strengthener containing Pistacia lentiscus and hyaluronic acid significantly improved the appearance and firmness of brittle nails in both in vitro and clinical settings.
4 citations
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September 2020 in “Andrologia” This study found that Origanum vulgare extract improved testicular structure and function in mice against finasteride-induced damage by enhancing antioxidant defense and modulating gene expression related to apoptosis.
July 2026 in “Current Stem Cell Reports” This review highlights that stem cell-based therapies show promise in skin regeneration for conditions like chronic wounds and burns due to their regenerative and immunomodulatory effects, though challenges like safety and scalability limit widespread clinical use.
July 2026 in “Journal of the American Academy of Dermatology” Bovine colostrum may improve hair and skin health.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review found that hair loss is nearly universal by mid-life, significantly impacts psychological well-being, especially for women, and that users often discontinue the leading treatment, minoxidil, due to adherence issues.
June 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review highlights that hair loss is nearly universal by mid-life, poses significant psychological burdens, particularly for women, and shows that many discontinue minoxidil due to adherence challenges.
April 2026 in “International Journal of Molecular Sciences” This narrative review highlights the need for diabetes-informed approaches to aesthetic dermatology as accelerated skin aging in diabetic patients complicates the safety and effectiveness of cosmetic procedures.
March 2026 in “Preprints.org” This study reviews how individuals with diabetes experience accelerated skin aging and explores the implications for cosmetic treatments, highlighting the need for diabetes-informed dermatologic approaches due to limited evidence on safety and efficacy in this population.
October 2025 in “Frontiers in Pharmacology” This review explores the immunopharmacological potential of A. lappa for inflammatory musculoskeletal disorders (IMSDs) but reports no new clinical results, emphasizing the need for standardized research methodologies.
This review suggests that combining Platelet-Rich Plasma and microneedling may enhance hair restoration outcomes in patients with androgenetic alopecia compared to using either therapy alone.
November 2024 in “SKIN The Journal of Cutaneous Medicine” This study found that generic quality of life questionnaires, like the SF-36 and DLQI, are not sensitive enough to detect differences in health-related quality of life between patients with varying severity of alopecia areata.
August 2024 in “Journal of Clinical Medicine” This review examines quality control in preparing platelet-rich plasma, highlighting knowledge gaps in its clinical efficacy and safety, but reports no new clinical results.
January 2024 in “Faculty of 1000 Research Ltd” This study found that aesthetic plastic surgeons in Guangdong, China, show strong interest in continuing education, with varied preferences based on the type of hospital they work in.
January 2023 in “Faculty of 1000 Research Ltd” This study found a strong interest among aesthetic plastic surgeons in Guangdong, China, for further training courses, with significant differences in training preferences between private and government hospital surgeons.
January 2022 in “International Journal of Frontiers in Medicine” In this study, the researchers explored the traditional Chinese medicine approach to treating seborrheic alopecia, emphasizing the interplay between zang-fu organs, qi, blood, and body fluids, and highlighted treatments focusing on wind, dampness, heat, blood stasis, and deficiency.