Immunopharmacological Potential of Arctium Lappa L. in Immune-Mediated Skin Diseases: A Critical Review of Experimental and Clinical Evidence

    October 2025 in “ Frontiers in Pharmacology
    Mengyao Yang, Ge Peng, Alafate Abudouwanli, Shan Wang, Quan Sun, Wanchen Zhao, Yi Jayne Tan, Xuefei Du, Zhang Li, Hideoki Ogawa, Ko Okumura, Xinghua Gao, François Niyonsaba
    TLDR Arctium lappa L. might help treat immune-related skin diseases, but more research is needed.
    Arctium lappa L. demonstrates potential for treating immune-mediated skin diseases (IMSDs), but current evidence is preliminary due to inconsistencies in extract preparation, lack of standardized dosing, and absence of robust randomized clinical trials. Future research should focus on standardized phytochemical characterization, translational animal models, pharmacokinetic studies, and controlled clinical trials to confirm its efficacy and safety.
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