research Advancing Skin Model Development: A Focus on a Self-Assembled, Induced Pluripotent Stem Cell-Derived, Xeno-Free Approach
A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
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research Strategies for the Synthesis of Heterocycles and Their Applications
Methods for creating diverse ring-shaped molecules and their uses.
research Cyberspace Chat: When Finasteride Suddenly Stops Working—Is It Counterfeit?
Some generic finasteride may be counterfeit, leading to less effectiveness and increased hair loss.
research Proliferative and Non-Proliferative Lesions of the Rat and Mouse Integument
The project created a standardized system for classifying skin lesions in lab rats and mice.
research Monitoring of Clinical Signs in Goats with Transmissible Spongiform Encephalopathies
Goats with BSE or scrapie show varying symptoms, and using only clinical signs may not detect all scrapie cases.
research Non-Viral Delivery of the CRISPR/Cas System: DNA Versus RNA Versus RNP
RNA delivery is best for in-body use, while RNP delivery is good for outside-body use. Both methods are expected to greatly impact future treatments.
research Association of Lifelong Intake of Barley Diet with Healthy Aging: Changes in Physical and Cognitive Functions and Intestinal Microbiome in Senescence-Accelerated Mouse-Prone 8 (SAMP8)
Eating barley for life may lead to healthier aging in mice.
research Maternal Iron Status in Early Pregnancy and DNA Methylation in Offspring: An Epigenome-Wide Meta-Analysis
A mother's iron levels early in pregnancy can influence the DNA makeup of her child, potentially affecting the child's health.
research Directed Elimination of Senescent Cells by Inhibition of BCL-W and BCL-XL
Blocking specific proteins can help remove aging cells and might treat age-related diseases and promote hair growth.
research New Developments in Our Understanding of Acne Pathogenesis and Treatment
We now understand more about what causes acne and this could lead to better, more personalized treatments.
research Hair Follicle Pigmentation: Mechanisms and Factors Influencing Melanin Production
Hair color is determined by melanin produced and transferred in hair follicles.
research The Immunology of the Porcine Skin and Its Value as a Model for Human Skin
Porcine skin is very similar to human skin, making it a useful model for research.
research C-Myc Activation in Transgenic Mouse Epidermis Results in Mobilization of Stem Cells and Differentiation of Their Progeny
c-Myc activation in mouse skin increases sebaceous gland growth and affects hair follicle development.
research Fibroblast Growth Factors: Key Players in Regeneration and Tissue Repair
Fibroblast Growth Factors (FGFs) are important for tissue repair and regeneration, influencing cell behavior and other factors involved in healing, and are crucial in processes like wound healing, bone repair, and hair growth.
research Cantú Syndrome Is Caused by Mutations in ABCC9
Cantú syndrome is caused by mutations in the ABCC9 gene.
research Wounding Induces Dedifferentiation of Epidermal Gata6+ Cells and Acquisition of Stem Cell Properties
Wounded skin cells can revert to stem cells and help heal.
research Epidermal Wnt/β-Catenin Signaling Regulates Adipocyte Differentiation via Secretion of Adipogenic Factors
Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.
research Reprogramming Adult Dermis to a Neonatal State Through Epidermal Activation of Beta-Catenin
Activating a protein called β-catenin in adult skin can make it behave like young skin, potentially helping with skin aging and hair loss.
research The Vitamin D Receptor Is a Wnt Effector That Controls Hair Follicle Differentiation and Specifies Tumor Type in Adult Epidermis
Vitamin D receptor helps control hair growth and could be used to treat certain skin tumors.
research Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome
Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.
research Metabolites From Macroalgae and Its Applications in the Cosmetic Industry: A Circular Economy Approach
Macroalgae compounds offer sustainable, effective benefits for cosmetics.
research Cutaneous Permeation And Penetration Of Sunscreens: Formulation Strategies And In Vitro Methods
Effective sunscreen formulations can reduce skin absorption and enhance protection.
research Dissolving Microneedles: Applications and Growing Therapeutic Potential
Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.
research Who Do We Invent For? Patents by Women Focus More on Women’s Health, but Few Women Get to Invent
Women inventors focus more on women's health, but there are few of them.
research Therapeutics for COVID-19 and Post COVID-19 Complications: An Update
New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.
research Human Epidermal Neural Crest Stem Cells as a Source of Schwann Cells
Human Schwann cells can be quickly made from hair follicle stem cells for nerve repair.
research Gene Therapy to Enhance Angiogenesis in Chronic Wounds
Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.
research Ritlecitinib And Brepocitinib Demonstrate Significant Improvement In Scalp Alopecia Areata Biomarkers
Two drugs, ritlecitinib and brepocitinib, improved scalp hair loss condition markers.
research Gab1 and MAPK Signaling Are Essential in the Hair Cycle and Hair Follicle Stem Cell Quiescence
Gab1 protein is crucial for hair growth and stem cell renewal, and Mapk signaling helps maintain these processes.
research Multipotent Nestin-Positive Stem Cells Reside in the Stroma of Human Eccrine and Apocrine Sweat Glands and Can Be Propagated Robustly In Vitro
Human sweat glands have a type of stem cell that can grow well and turn into different cell types.