11 citations
,
October 2019 in “Journal of Cancer Immunology” This article discusses the role of external beam radiotherapy as a primary treatment method for cancer and reports no new clinical findings.
6 citations
,
February 2009 in “Journal of Investigative Dermatology”
This study observed that combining PRP and Tressfix Serum significantly improved hair regrowth and reduced microRNA expression linked to Chronic Telogen Effluvium compared to using either treatment alone.
56 citations
,
August 2019 in “Clinical, Cosmetic and Investigational Dermatology” This essay discusses telogen effluvium, the issues surrounding its diagnosis and differentiation from other forms of hair loss, and emphasizes the need for empathetic patient care; it reports no new clinical findings.
April 2018 in “Journal of Investigative Dermatology” This study found that the loss of transcription factor Ovol2 in epidermal and hair follicle stem cells leads to migration defects, which are partially improved by deleting the EMT-inducing Zeb1.
164 citations
,
December 1984 in “Proceedings of the National Academy of Sciences” This study found that TCDD significantly reduced EGF receptor binding in various animal models, linked to toxic symptoms like weight loss and developmental delays, with receptor phosphorylation persisting several days.
In this study, human dermal papilla cell-derived extracellular vesicles (hDPC-EVs) were found to reduce skin fibrosis in mice by delivering miRNA-182-5p, which inhibits the TGF-β1 signaling pathway.
80 citations
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June 2008 in “Biomaterials” This study found that poly(ethylene-co-vinyl alcohol) membranes support the self-assembly of dermal papilla cells into compact spheroidal microtissues capable of inducing new hair follicles, suggesting potential for large-scale production for hair follicle regeneration.
In this study, researchers developed de novo designed hetero-bifunctional proteins as an alternative approach for targeted protein degradation, successfully targeting BCL-xL for degradation in cells and inducing apoptosis, which may expand the range of addressable E3 ligases and disease targets.
January 1999 in “American Journal of Medical Genetics Part A” This case report describes a rare occurrence of ectodermal dysplasia features in a 14-year-old with MBTPS1 gene variants, expanding the known spectrum of related disorders.
10 citations
,
June 2019 in “Transplant infectious disease” This case study reported TSPyV DNA detection in blood and urine samples before trichodysplasia spinulosa skin lesions developed in a kidney transplant patient under immunosuppressive therapy.
52 citations
,
October 2007 in “Molecular Therapy” Injecting lentiviral vectors into early gestation mice effectively targets skin stem cells for potential gene therapy.
2 citations
,
February 2014 in “Animal Biotechnology” This study reported that the PTGER2 gene is strongly expressed in cashmere goat skin and its expression tends to decrease from the anagen to telogen stages of the hair follicle cycle.
September 2025 in “Animals” This study identified novel genetic variations in the KRTAP22-2 gene among eight sheep breeds but found no association between these genotypes and wool fibre traits, indicating possible species-specific differences compared to goats.
2 citations
,
September 2025 in “International Journal of Nanomedicine” This review discusses the roles of extracellular vesicles in skin health and disease and reports no clinical results; the authors highlight potential therapeutic uses and call for more research.
2 citations
,
October 2019 in “Dermatologic Therapy” This study suggests using a handheld dermatoscope may allow for simple and efficient differentiation of eruptive vellus hair cysts by detecting vellus hair shafts, as demonstrated in a familial case involving five women.
45 citations
,
September 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” This study found that deleting β-catenin in epidermis-specific VDR knockout mice did not prevent UVB-induced skin tumors, indicating β-catenin does not compensate for VDR's role in tumor suppression.
July 2024 in “Reactions Weekly”
3 citations
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August 2021 in “Research Square (Research Square)” This study found that increased mRNA expression of the Ectodysplasin-A2-Receptor, observed across multiple species and tissues, may exacerbate inflammation during aging, suggesting potential benefits of blocking EDA2R/EDA-A2 signaling.
January 2022 in “International Journal of Medicine in Developing Countries” In this study, 35.4% of telogen effluvium patients showed ferritin deficiency and 34.2% had vitamin D deficiency, suggesting these should be included in TE screening; TSH testing should be individualized.
December 2024 in “Medical alphabet” This article reviews current knowledge about diffuse telogen effluvium, focusing on its classification, clinical features, causes, and diagnostic and treatment approaches.
February 2026 in “BMJ Open” In this assessment of existing research on DTC commercial virtual care, it is highlighted that impacts on care quality, health outcomes, system use, and privacy ethics remain unclear, with potential bias noted due to industry financial connections.
54 citations
,
October 2022 in “Cells” This review discusses the therapeutic potential of mesenchymal stem cell-derived extracellular vesicles and modern technologies like 3D bioprinting but reports no new clinical results.
12 citations
,
September 2020 in “Stem cell research & therapy” This study concluded that early-stage tissue-engineered skin substitutes, developed using skin progenitor cells, had a better graft efficiency and supported hair follicle formation, which may improve wound healing outcomes.
6 citations
,
June 2021 in “Developmental biology” This study found that dermal EZH2 plays a crucial role in controlling fibroblast differentiation by regulating Wnt/β-catenin and retinoic acid signaling during skin development.
40 citations
,
August 2021 in “JAAD international” This review found that teledermatology was significantly used during the COVID-19 pandemic, particularly for managing common ambulatory dermatoses like acne and eczema.
2 citations
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May 2018 in “Dermatologic Surgery” This overview outlines the Dermatologic Surgery journal's comprehensive focus on cosmetic and reconstructive procedures, but it does not present any new research findings.
43 citations
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April 1996 in “Journal of Investigative Dermatology” 1 citations
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May 2019 in “International Journal of Applied Pharmaceutics” This study evaluated hair tonic and gel formulations containing Angiopteris evecta root water extract and found both fulfilled pharmaceutical preparation standards, with the 12.5% hair tonic and 10.0% gel concentrations most effective for hair growth without a significant difference in performance.
November 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that the Polycomb Repressive Complex 2, particularly its component Ezh2, is crucial in regulating dermal fibroblast differentiation and epidermal keratinocyte proliferation during murine skin development.