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The skin acts like an endocrine organ, producing hormones that affect various body functions and skin health, and understanding this can lead to new treatments.

More research is needed to understand how testosterone is maintained in adult males.

The research found that male pattern hair loss is mostly genetic and involves hair thinning due to hormonal effects and changes in gene expression.

Bovine milk-derived exosomes may improve skin, hair, gut, brain, and bone health.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

Trapa bispinosa Roxb. extract may help reduce prostate size and cell growth in BPH.

Different genes cause Female Pattern Hair Loss compared to male hair loss, and treatments vary, but more research is needed to understand it fully.

Dutasteride injections can help hair growth in androgenic alopecia but need more research for long-term use.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Epidermal Wnt/β-catenin signaling controls fat cell formation and hair growth.

Licorice has many health benefits but should be used carefully due to possible side effects.

Chemotherapy damages hair follicles, causing hair loss and other cellular changes.

Chitosan, a natural substance, can be used to create tiny particles that effectively deliver various types of drugs, but more work is needed to improve stability and control of drug release.

PCOS management includes lifestyle changes and medications, with ongoing research into repurposed drugs for better treatment options.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Lysophospholipids like LPA and S1P are important for hair growth, immune responses, and vascular development, and could be targeted for treating diseases.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

Disrupting β-catenin signaling in certain cells causes anorectal malformations.

TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Proxalutamide improved recovery, lowered death rates, and reduced hospital stay for COVID-19 patients.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Hormone therapy for prostate cancer can increase heart risks, especially in men with heart conditions.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Growth hormone levels affect hair growth and loss, with too much causing excess hair and too little leading to hair loss.

Fenugreek leaf extracts significantly promoted hair growth in mice with alopecia.

Dexpanthenol helps human hair follicle cells grow by preventing aging and death, and by supporting growth signals.

Laminin 332 is essential for normal skin cell behavior and structure.

Gut microbes significantly affect brain steroid levels.