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Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

A high-fat diet caused severe health problems in female macaques but was reversible with a normal diet, while male macaques reacted differently.

Eating high-glycemic and dairy foods can increase hormones that may cause acne and other health issues.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.

Understanding phenotypic plasticity is crucial for developing effective cancer therapies.

The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.

Certain proteins, Lgr5 and Lgr6, are important markers of adult stem cells and are involved in tissue repair and cancer development.

Alopecia areata is an autoimmune condition causing hair loss, influenced by genetics, stress, and diet, and may be prevented by a high soy oil diet.

Vitamin D receptor interacts with certain dietary components to help prevent diseases and regulate hair growth.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Androgens can both increase and decrease hair growth in different parts of the body.

Early development of hair, teeth, and glands involves specific signaling pathways and cellular interactions.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Men's sensitivity to male hormones might affect how severe COVID-19 gets for them.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

PDGFA/AKT signaling is important for the growth and maintenance of certain skin fat cells.