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Human sebaceous glands can grow normally for a week without certain growth factors, and adding estrogen reduces their oil production without affecting cell growth.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Estrogens help reduce skin aging, and SERMs might offer similar benefits without the risks of hormone therapy.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Excess androgens may cause PCOS, not just be a symptom.

Testosterone's effects on COVID-19 are unclear and need more research.

Estrogen therapy can reduce skin aging but has cancer risks.

Women generally handle heart enlargement better than men, but it's riskier for them if it occurs; hormones like estrogen offer some protection.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Men and women experience skin aging differently due to changes in sex hormone levels with age.

Postpartum depression is linked to changes in brain chemicals, inflammation, stress, and certain genes, and can potentially be identified by markers like specific steroids, serotonin levels, and vitamin D levels.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Testosterone therapy can improve sexual desire and function in postmenopausal women but should be used cautiously and not based solely on testosterone levels.

Ethinylestradiol/chlormadinone acetate may be an effective and well-tolerated treatment for skin conditions caused by excess androgens.

No treatment fully stops excessive hair growth in women, but various methods can help manage it effectively.

Estrogen-progestin contraception lowers ovarian, endometrial, and colon cancer risk but may raise breast and cervical cancer risk, helps with menstrual and acne issues, and new methods are as effective as pills. Metformin helps overweight women with PCOS and insulin resistance, and dopamine agonists treat prolactinomas.

Menopause causes dry skin, wrinkles, and hair changes, with hormone therapy helping but not recommended just for these issues.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Testosterone helps human pancreatic cells increase insulin release.

Both estrogens and androgens are important for health in both males and females.

PCOS in teen girls should be managed with lifestyle changes and sometimes medication to improve symptoms and health.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Estrogen and androgenic hair increase melanoma risk, especially in European-ancestry individuals.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Finasteride reduces inflammation and improves immune response after trauma by altering hormone levels.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Castration significantly reduces prostate size and BPH symptoms.

Bilateral Orchiectomy effectively reduces the need for anti-androgen medication in most transgender females.